Anti-Her2/ERBB2 Antibody, Rabbit Polyclonal

Anti-Her2/ERBB2 Antibody, Rabbit Polyclonal の製品情報

Anti-Her2/ERBB2 Antibody, Rabbit Polyclonal
Reacts with: Mouse
Mouse Her2/ERBB2
Recombinant Mouse HER2 / ErbB2 protein (Catalog#50714-M08H)
Produced in rabbits immunized with purified, recombinant Mouse HER2 / ErbB2 (Catalog#50714-M08H; P70424; Met1-Thr653). HER2 / ErbB2 specific IgG was purified by Mouse HER2 / ErbB2 affinity chromatography.
Polyclonal Rabbit IgG
Protein A & Antigen Affinity
0.2 μm filtered solution in PBS
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Anti-Her2/ERBB2 Antibody, Rabbit Polyclonal 検証済のアプリケーション

アプリケーション 推奨希釈率/用量
WB 1:500-1:1000
ELISA 1:25000-1:50000
Please Note: Optimal concentrations/dilutions should be determined by the end user.

Anti-Her2/ERBB2 Antibody, Rabbit Polyclonal の画像

Anti-ERBB2 rabbit polyclonal antibody at 1:500 dilution

Lane A: Hela Whole Cell Lysate

Lysates/proteins at 30 μg per lane.


Goat Anti-Rabbit IgG H&L (Dylight800) at 1/10000 dilution.

Developed using the Odyssey technique.

Performed under reducing conditions.

Predicted band size:138 kDa

Observed band size:138 kDa

Anti-Her2/ERBB2 Antibody, Rabbit Polyclonal: 別名

Anti-c-erbB2 Antibody; Anti-c-neu Antibody; Anti-Erbb-2 Antibody; Anti-HER-2 Antibody; Anti-HER2 Antibody; Anti-l11Jus8 Antibody; Anti-mKIAA3023 Antibody; Anti-Neu Antibody

Her2/ERBB2 背景情報

Human epidermal growth factor receptor 2 (HER2), also known as ErbB2, NEU, and CD340, is a type I membrane glycoprotein and belongs to the epidermal growth factor (EGF) receptor family. HER2 protein cannot bind growth factors due to the lacking of ligand binding domain of its own and autoinhibited constitutively. However, HER2 forms a heterodimer with other ligand-bound EGF receptor family members, therefore stabilizes ligand binding and enhances kinase-mediated activation of downstream molecules. HER2 plays a key role in development, cell proliferation and differentiation. HER2 gene has been reported to associate with malignancy and a poor prognosis in numerous carcinomas, including breast, prostate, ovarian, lung cancers and so on.
erb-b2 receptor tyrosine kinase 2
  • Krawczyk N, et al. (2009) HER2 status on persistent disseminated tumor cells after adjuvant therapy may differ from initial HER2 status on primary tumor. Anticancer Res. 29(10): 4019-24.

Standard Antibody Development Service

Rabbit MAb

Mouse MAb

Rabbit PAb

Fast Antibody Development Service

Mouse MAb

Rabbit PAb

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