Recombinant Anti-ECM1 Antibody, Rabbit Monoclonal

RRID Number: AB_2860501
EliteRmab®, manufactured by recombinant technology

Recombinant Anti-ECM1 Antibody, Rabbit Monoclonal の製品情報

製品名
Recombinant Anti-ECM1 Antibody, Rabbit Monoclonal
検証済のアプリケーション
ELISA
交差反応
Reacts with: Mouse
特異性
Mouse ECM1
No cross-reactivity in ELISA with
Human ECM1
免疫原
Recombinant Mouse ECM1 protein (Catalog#50331-M08H)
調製
This antibody was obtained from a rabbit immunized with purified, recombinant Mouse ECM1 (rM ECM1; Catalog#50331-M08H; Q61508-1; Met 1-Glu 559).
ソース
Monoclonal Rabbit IgG Clone #038
精製
Protein A
緩衝液
0.2 μm filtered solution in PBS
標識物
Unconjugated
状態
Liquid
配送方法
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
保存条件
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Recombinant Anti-ECM1 Antibody, Rabbit Monoclonal 検証済のアプリケーション

アプリケーション 推奨希釈率/用量
ELISA 1:5000-1:10000
Please Note: Optimal concentrations/dilutions should be determined by the end user.

Recombinant Anti-ECM1 Antibody, Rabbit Monoclonal: 別名

Anti-AI663821 Antibody; Anti-p85 Antibody

ECM1 背景情報

Extracellular matrix protein 1 (ECM1) is a secreted glycoprotein and playing a pivotal role in endochondral bone formation, angiogenesis, and tumour biology. Three splice variants have been identified: ECM1a (540 aa) is most widely expressed, with highest expression in the placenta and heart; ECM1b (415 aa) is differentiation-dependent expressed and found only in tonsil and associated with suprabasal keratinocytes; ECM1c (559 aa) accounts for approximately 15% of skin ECM1. Although ECM1 is not tumor specific, is significantly elevated in many malignant epithelial tumors and is suggested as a possible trigger for angiogenesis, tumor progression and malignancies. It also has been shown to regulate endochondral bone formation, skeletal development and tissue remodeling.
完全な名称
extracellular matrix protein 1
参考文献
  • Oyama N, et al. (2003) Autoantibodies to extracellular matrix protein 1 in lichen sclerosus. Lancet. 362(9378): 118-23.
  • Chan I, et al. (2004) Rapid diagnosis of lipoid proteinosis using an anti-extracellular matrix protein 1 (ECM1) antibody. J Dermatol Sci. 35(2): 151-3.
  • Lupo I, et al. (2005) A novel mutation of the extracellular matrix protein 1 gene (ECM1) in a patient with lipoid proteinosis (Urbach-Wiethe disease) from Sicily. Br J Dermatol. 153(5): 1019-22.
  • Sander CS, et al. (2006) Expression of extracellular matrix protein 1 (ECM1) in human skin is decreased by age and increased upon ultraviolet exposure. Br J Dermatol. 154(2): 218-24.

Standard Antibody Development Service

Rabbit MAb

Mouse MAb

Rabbit PAb

Fast Antibody Development Service

Mouse MAb

Rabbit PAb

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