Anti-NKp30/NCR3 Antibody, Rabbit Polyclonal

Anti-NKp30/NCR3 Antibody, Rabbit Polyclonal の製品情報

製品名
Anti-NKp30/NCR3 Antibody, Rabbit Polyclonal
検証済のアプリケーション
ELISA
交差反応
Reacts with: Human
特異性
Human NKp30/NCR3
免疫原
Recombinant Human NCR3 protein (Catalog#10480-H08H)
調製
Produced in rabbits immunized with purified, recombinant Human NCR3 / NKp30 extracellular domain (rh NCR3; Catalog#10480-H08H; NP_667341.1; Met 1-Gly 135). NCR3 specific IgG was purified by human NCR3 affinity chromatography.
ソース
Polyclonal Rabbit IgG
精製
Protein A & Antigen Affinity
緩衝液
0.2 μm filtered solution in PBS
標識物
Unconjugated
状態
Liquid
配送方法
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
保存条件
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Anti-NKp30/NCR3 Antibody, Rabbit Polyclonal 検証済のアプリケーション

アプリケーション 推奨希釈率/用量
ELISA 1:1000-1:2000
Please Note: Optimal concentrations/dilutions should be determined by the end user.

Anti-NKp30/NCR3 Antibody, Rabbit Polyclonal: 別名

Anti-1C7 Antibody; Anti-CD337 Antibody; Anti-DAAP-90L16.3 Antibody; Anti-LY117 Antibody; Anti-MALS Antibody; Anti-NCR3 Antibody; Anti-NKp30 Antibody

NKp30/NCR3 背景情報

Natural Cytotoxicity Triggering Receptor 3, NCR3, also known as NKp30, or CD337, is a natural cytotoxicity receptor, expressed on subsets of human peripheral blood NK cells, involved in NK cell killing of tumor cells and immature dendritic cells. The cellular ligand for NKp30 has remained elusive, but the membrane-associated heparan sulfate (HS) proteoglycans are involved in the recognition of cellular targets by NKp30 was recently reported. NKp30 is a member of the immunoglobulin superfamily and one of three existing natural cytotoxicity-triggering receptors. NKp30 is a glycosylated protein and is thought to be selectively expressed in resting and activated natural killer cells. NKp30 is a stimulatory receptor on human NK cells implicated in tumor immunity and is capable of promoting or terminating dendritic cell maturation. NCR3 may play a role in inflammatory and infectious diseases.
完全な名称
natural cytotoxicity triggering receptor 3
参考文献
  • Warren HS, et al. (2005) Evidence that the cellular ligand for the human NK cell activation receptor NKp30 is not a heparan sulfate glycosaminoglycan. J Immunol. 175(1): 207-12.
  • Mulcahy H, et al. (2006) LST1 and NCR3 expression in autoimmune inflammation and in response to IFN-gamma, LPS and microbial infection. Immunogenetics. 57(12): 893-903.
  • Hsieh CL, et al. (2006) NKp30 is a functional activation receptor on a subset of rat natural killer cells. Eur J Immunol. 36(8): 2170-80.
  • Ponnampalam AP, et al. (2008) Identification and hormonal regulation of a novel form of NKp30 in human endometrial epithelium. Eur J Immunol. 38(1): 216-26.

Standard Antibody Development Service

Rabbit MAb

Mouse MAb

Rabbit PAb

Fast Antibody Development Service

Mouse MAb

Rabbit PAb

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