Recombinant Anti-Galectin 3/LGALS3 Antibody, Rabbit Monoclonal

RRID Number: AB_2860127
EliteRmab®, manufactured by recombinant technology

Recombinant Anti-Galectin 3/LGALS3 Antibody, Rabbit Monoclonal の製品情報

製品名
Recombinant Anti-Galectin 3/LGALS3 Antibody, Rabbit Monoclonal
検証済のアプリケーション
IHC-P
交差反応
Reacts with: Human
特異性
Human Galectin 3/LGALS3
No cross-reactivity in ELISA with
Human Galectin-1 / LGALS1
Human Galectin-7 / LGALS7
Human Galectin-8 / LGALS8
免疫原
Recombinant Human Galectin-3 / LGALS3 protein (Catalog#10289-HNAE)
調製
This antibody was obtained from a rabbit immunized with purified, recombinant Human Galectin-3 / LGALS3 (rh Galectin-3 / LGALS3; Catalog#10289-HNAE; P17931; Met1-Ile250).
ソース
Monoclonal Rabbit IgG Clone #102
精製
Protein A
緩衝液
0.2 μm filtered solution in PBS
標識物
Unconjugated
状態
Liquid
配送方法
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
保存条件
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Recombinant Anti-Galectin 3/LGALS3 Antibody, Rabbit Monoclonal 検証済のアプリケーション

アプリケーション 推奨希釈率/用量
IHC-P 1:100-1:500
Please Note: Optimal concentrations/dilutions should be determined by the end user.

Recombinant Anti-Galectin 3/LGALS3 Antibody, Rabbit Monoclonal の画像

Immunochemical staining of human Galectin3 in human lung with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections).
Immunochemical staining of human Galectin3 in human colon carcinoma with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections).

Recombinant Anti-Galectin 3/LGALS3 Antibody, Rabbit Monoclonal: 別名

Anti-CBP35 Antibody; Anti-GAL3 Antibody; Anti-GALBP Antibody; Anti-GALIG Antibody; Anti-L31 Antibody; Anti-LGALS2 Antibody; Anti-MAC2 Antibody

Galectin 3/LGALS3 背景情報

LGALS3 (Galectin 3) is a Protein Coding gene. This gene encodes a member of the galectin family of carbohydrate-binding proteins. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. LGALS3 is a beta-galactoside-binding lectin and plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion, and T-cell regulation. LGALS3 has an important role in tumor progression through inhibition of apoptosis. LGALS3 expression is associated with neoplastic transformation and with differentiation of monocytes to macrophages. Elevated expression of LGALS3 has been demonstrated in the synovium of rheumatoid arthritis (RA). Diseases associated with LGALS3 include Follicular Adenoma and Papillary Carcinoma.
完全な名称
lectin, galactoside-binding, soluble, 3
参考文献
  • Dumic J, et al. (2006) Galectin-3: an open-ended story. Biochim Biophys Acta. 1760(4): 616-35.
  • Sharma UC, et al. (2004) Galectin-3 marks activated macrophages in failure-prone hypertrophied hearts and contributes to cardiac dysfunction. Circulation. 110(19): 3121-8.
  • Yan YP, et al. (2009) Galectin-3 mediates post-ischemic tissue remodeling. Brain Res. 1288: 116-24.

Standard Antibody Development Service

Rabbit MAb

Mouse MAb

Rabbit PAb

Fast Antibody Development Service

Mouse MAb

Rabbit PAb

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