Recombinant Anti-Factor D Antibody, Rabbit Monoclonal

EliteRmab®, manufactured by recombinant technology

Recombinant Anti-Factor D Antibody, Rabbit Monoclonal の製品情報

製品名
Recombinant Anti-Factor D Antibody, Rabbit Monoclonal
検証済のアプリケーション
ELISA
交差反応
Reacts with: Human
特異性
Human Factor D
免疫原
Recombinant Human Adipsin / Complement Factor D protein (Catalog#10160-H08H)
調製
This antibody was obtained from a rabbit immunized with purified, recombinant Human Adipsin / Complement Factor D (rh Adipsin / Complement Factor D; Catalog#10160-H08H; P00746; Ile26-Ala253).
ソース
Monoclonal Rabbit IgG Clone #005
精製
Protein A
緩衝液
0.2 μm filtered solution in PBS
標識物
Unconjugated
状態
Liquid
配送方法
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
保存条件
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Recombinant Anti-Factor D Antibody, Rabbit Monoclonal 検証済のアプリケーション

アプリケーション 推奨希釈率/用量
ELISA 1:5000-1:10000
Please Note: Optimal concentrations/dilutions should be determined by the end user.

Recombinant Anti-Factor D Antibody, Rabbit Monoclonal: 別名

Anti-ADIPSIN Antibody; Anti-ADN Antibody; Anti-DF Antibody; Anti-FACTOR D Antibody; Anti-PFD Antibody

Factor D 背景情報

Complement factor D, also known as Adipsin, C3 convertase activator, Properdin factor D and CFD is a secreted protein which belongs to thepeptidase S1 family. CFD / Adipsin contains onepeptidase S1 domain. Complement factor D ( CFD / Adipsin ) is a component of the alternative complement pathway best known for its role in humoral suppression of infectious agents. Complement factor D ( CFD / Adipsin ) has a high level of expression in fat, suggesting a role for adipose tissue in immune system biology. This protein is also a serine protease that is secreted by adipocytes into the bloodstream. Complement factor D ( CFD / Adipsin ) cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Its function is homologous to that of C1s in the classical pathway. Complement factor D ( CFD / Adipsin ) is a serine protease that stimulates glucose transport for triglyceride accumulation in fats cells and inhibits lipolysis. Defects in CFD / Adipsin are the cause of complement factor D deficiency (CFD deficiency) which predisposes to invasive meningococcal disease.
完全な名称
complement factor D (adipsin)
Related Pathways
  • Complement Activation Pathways
    Complement Activation Pathways
参考文献
  • Volanakis JE, et al.,1996, Protein Sci. 5 (4): 553-64.
  • Searfoss,G.H et al., 2003, J Biol Chem. 278 (46):46107-16.
  • Ukkola,O. et al., 2003, Eur J Clin Nutr. 57 (9):1073-8.
  • Ronti T, et al., 2006, Clin. Endocrinol. (Oxf) 64 (4): 355-65.

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Mouse MAb

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