FGF1 cDNA ORF Clone in Cloning Vector, Human

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FGF1 cDNA ORF Clone in Cloning Vector, Human: 製品情報

遺伝子
Human
遺伝子の長さ
468 bp
シーケンスの特徴
A number of silent mutations were introduced into the DNA sequence in order to increase its protein expression level in E. coli system.The translated amino acid sequence is identical with NP_000791.1.
製品の特徴
Full length Clone DNA of Human fibroblast growth factor 1 (acidic).
プラスミド
ベクター
シークエンシングプライマー
M13-47 and RV-M
品質管理
The plasmid is confirmed by full-length sequencing.
スクリーニング
細菌スクリーニング抵抗力
Ampicillin
保存 & 配送
配送方法
Each tube contains lyophilized plasmid.
保存条件
The lyophilized plasmid can be stored at ambient temperature for three months.

FGF1 cDNA ORF ヌクレオチド配列およびアミノ酸配列に関する情報

**Sino Biological guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories.**

FGF1 cDNA ORF Clone in Cloning Vector, Human: 別名

AFGF cDNA ORF Clone, Human; ECGF cDNA ORF Clone, Human; ECGF-beta cDNA ORF Clone, Human; ECGFA cDNA ORF Clone, Human; ECGFB cDNA ORF Clone, Human; FGF-1 cDNA ORF Clone, Human; FGF-alpha cDNA ORF Clone, Human; FGFA cDNA ORF Clone, Human; GLIO703 cDNA ORF Clone, Human; HBGF-1 cDNA ORF Clone, Human; HBGF1 cDNA ORF Clone, Human

FGF1 背景情報

aFGF, also known as FGF1 and HBGF-1, is a member of the fibroblast growth factor family. The biological activity of aFGF protein is exerted through binding to four high affinity cell surface receptors (FGFR1–4), which results in receptor dimerization and transphosphorylation in the tyrosine kinase domain. aFGF protein shows a wide range of endocrine-like activities. As a multiple function growth factor, this protein is involved in embryo development and tissue repair. Additionally, this protein is considered to function in several important physiological and pathological processes, such as embryonic development, morphogenesis, angiogenesis, wound healing and atheromatosis, carcinogenesis, development, and invasion of cancer.

References

完全な名称
fibroblast growth factor 1 (acidic)
参考文献
  • Jaye M., et al.,(1986), Human endothelial cell growth factor: cloning, nucleotide sequence, and chromosome localization. Science 233:541-545.
  • Mergia A., et al., (1989), Structural analysis of the gene for human acidic fibroblast growth factor.Biochem. Biophys. Res. Commun. 164:1121-1129.
  • Wang W.P., et al.,(1989), Cloning of the gene coding for human class 1 heparin-binding growth factor and its expression in fetal tissues.Mol. Cell. Biol. 9:2387-2395.
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