VPREB1 (タンパク質 | 抗体 | cDNA クローン | ELISA キット)

All VPREB1 reagents are produced in house and quality controlled, including 1 VPREB1 Antibody, 14 VPREB1 Gene, 1 VPREB1 qPCR. All VPREB1 reagents are ready to use.

VPREB1 関連の研究分野

VPREB1 の背景知識

VPREB1 gene, a component of the surrogate light chain of the pre-B-cell receptor (pre-BCR), have been observed in childhood B-cell acute lymphoblastic leukemia (B-ALL), and have been suggested to result from recombination activating gene (RAG) activation. Studies show that a low copy number of the VPREB1 gene is related to the pathogenesis of RA and other autoimmune disorders. Moreover, the VpreB1 can act as an enhancer to ensure developmental stage-specific expression of a reporter gene in B lymphocytes in vivo.