TAOK3 (タンパク質 | 抗体 | cDNA クローン | ELISA キット)

All TAOK3 reagents are produced in house and quality controlled, including 1 TAOK3 Antibody, 13 TAOK3 Gene, 1 TAOK3 Lysate, 1 TAOK3 Protein, 1 TAOK3 qPCR. All TAOK3 reagents are ready to use.

TAOK3 Protein (1)

    TAOK3 Antibody (1)

      TAOK3 cDNA Clone (13)

      NM_016281.3

      クローニングベクター cDNA 製品

      In lentiviral vector

      TAOK3 qPCR Primer (1)

      TAOK3 Lysate (1)

        TAOK3 の背景知識

        Serine/threonine-protein kinase TAO3, also known as cutaneous T-cell lymphoma-associated antigen HD-CL-9, CTCL-associated antigen HD-CL-9, Dendritic cell-derived protein kinase, JNK / SAPK-inhibitory kinase, Jun kinase-inhibitory kinase, Kinase from chicken homolog A, Thousand and one amino acid protein 3, JIK, TAOK3 and MAP3K18, is cytoplasm and peripheral membrane protein which belongs to theprotein kinase superfamily, STE Ser/Thr protein kinase family and STE2 subfamily. Protein kinases are pivotal regulators of cell signaling that modulate each other's functions and activities through site-specific phosphorylation events. TAOK3 / JIK contains oneprotein kinase domain. TAOK3 / JIK is ubiquitously expressed at a low level, and highly expressed in peripheral blood leukocytes (PBLs), thymus, spleen, kidney, skeletal muscle, heart and liver. TAOK3 / JIK inhibits the basal activity of Jun kinase. It is negatively regulated by epidermal growth factor (EGF). When overexpressed, TAOK3 / JIK may activate ERK1 / ERK2 and JNK / SAPK.

        TAOK3 の参考文献

        • Tassi E., et al., 1999, J. Biol. Chem. 274:33287-95.
        • Yoneda T., et al., 2001, J. Biol. Chem. 276:13935-40.
        • Yustein J.T., et al.,2003, Oncogene 22:6129-41.
        • Daub H., et al., 2008, Mol. Cell 31:438-48.

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