Syk (タンパク質 | 抗体 | cDNA クローン | ELISA キット)

All Syk reagents are produced in house and quality controlled, including 13 Syk Gene, 1 Syk qPCR. All Syk reagents are ready to use.

Syk の背景知識

SYK gene encodes a member of the family of non-receptor type Tyr protein kinases. This protein is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis. It is thought to be a modulator of epithelial cell growth and a potential tumour suppressor in human breast carcinomas. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Syk の参考文献

  • Boros K, Puissant A, Back M, et al. Increased SYK activity is associated with unfavorable outcome among patients with acute myeloid leukemia. Oncotarget. 2015;6(28):25575-25587.