Src (タンパク質 | 抗体 | cDNA クローン | ELISA キット)

All Src reagents are produced in house and quality controlled, including 1 Src Antibody, 44 Src Gene, 2 Src Lysate, 2 Src Protein, 2 Src qPCR. All Src reagents are ready to use.

Src Protein (2)

    Src Antibody (1)

      Src cDNA Clone (44)

      NM_005417.3

      クローニングベクター cDNA 製品

      In lentiviral vector

      In expression vector

      NM_001025395.2

      クローニングベクター cDNA 製品

      In lentiviral vector

      NM_009271.3

      クローニングベクター cDNA 製品

      In lentiviral vector

      Src Lysate (2)

        Src の背景知識

        Proto-oncogene tyrosine-protein kinase SRC is a hydrophobic protein belonging to the SRC family kinase including nine members that is a family of non-receptor tyrosine kinases. SRC protein may exist in different forms: C-SRC and V-SRC. C-SRC is only activated under certain circumstances where it is required such as growth factor signaling, while V-SRC is a constitutively active as opposed to normal SRC (C-SRC). Thus, V-SRC is an instructive example of an oncogene protein kinase whereas C-SRC is a proto-oncogene protein kinase. Inhibition of SRC with NR2A tyrosine phosphorylation mediated by PSD-95 may contribute to the lithium-induced downregulation of NMDA receptor function and provide neuroprotection against excitotoxicity.

        Src の参考文献

        • Juan Ma. et al., 2003, Neuroscience Letters. 348 (3): 185-189.
        • Czernilofsky AP. et al., 1980, Nature. 287: 198-203.
        • Beischlag TV. et al., 2002, Molecular and cellular biology. 22 (12): 4319-33.

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