RAB8B (タンパク質 | 抗体 | cDNA クローン | ELISA キット)

All RAB8B reagents are produced in house and quality controlled, including 1 RAB8B Antibody, 15 RAB8B Gene, 1 RAB8B qPCR. All RAB8B reagents are ready to use.

RAB8B 関連の研究分野

RAB8B の背景知識

RAB8B is an essential evolutionary conserved component of Wnt/beta-catenin signaling through regulation of LRP6 activity and endocytosis.RAB8B depletion reduces LRP6 activity, beta-catenin accumulation, and induction of Wnt target genes, whereas RAB8B overexpression promotes LRP6 activity and internalization and rescues inhibition of caveolar endocytosis.In Xenopus laevis and Danio rerio, RAB8B morphants show lower Wnt activity during embryonic development.