NCAM2 (タンパク質 | 抗体 | cDNA クローン | ELISA キット)

All NCAM2 reagents are produced in house and quality controlled, including 2 NCAM2 Antibody, 14 NCAM2 Gene, 2 NCAM2 Lysate, 2 NCAM2 Protein. All NCAM2 reagents are ready to use.

NCAM2 の背景知識

NCAM2 is a member of the immunoglobulin superfamily of cell adhesion molecules (IgCAMs).The neural cell adhesion molecule 2 (NCAM2) is encoded by a gene on chromosome 21 in humans.Neural cell adhesion molecules 2 (NCAM2/OCAM/RNCAM), is a paralog of NCAM1. The protein exists in a transmembrane and a lipid-anchored isoform, and has an ectodomain consisting of five immunoglobulin modules and two fibronectin type 3 homology modules. Structural models of the NCAM2 ectodomain reveal that it facilitates cell adhesion through reciprocal interactions between the membrane-distal immunoglobulin modules.NCAM (Neural Cell Adhesion Molecule) proteins are involved in axonal migration, synaptic formation and plasticity. Poor axonal growth and fasciculation is observed in animal models deficient for NCAM2.