Anti-TIM-1 / KIM-1 Antibody

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Anti-TIM-1 / KIM-1 Antibody (Mouse Monoclonal 抗体) の製品情報

Anti-TIM-1 / KIM-1 Antibody
Reacts with: Human
Human TIM-1 / KIM-1
No cross-reactivity in ELISA with
Mouse KIM1
Human TIMD3
Rat KIM1
Human TIMD4
Human cell lysate (293 cell line)
Recombinant Human KIM-1 / TIM1 / HACVR1 protein (Catalog#11051-H07H)
This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human KIM-1 / TIM1 / HACVR1 (rh KIM-1 / TIM1 / HACVR1; Catalog#11051-H07H; AAC39862.1; Ser 21-Gly 290). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
Monoclonal Mouse IgG1 Clone #10B8C11
Protein A
0.2 μm filtered solution in PBS
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Anti-TIM-1 / KIM-1 Antibody (Mouse Monoclonal 抗体) 検証済のアプリケーション

アプリケーション 推奨希釈率/用量
ELISA 1:1000-1:2000
ELISA(Det) 1:1000-1:10000
ELISA(Det): This antibody will detect Human KIM-1 / TIM1 / HACVR1 in ELISA pair set (Catalog: # SEK11051). In a sandwich ELISA, it can be used as detection antibody when paired with (Catalog: # 11051-MM06).
Please Note: Optimal concentrations/dilutions should be determined by the end user.

Anti-TIM-1 / KIM-1 Antibody: 別名

Anti-CD365 Antibody; Anti-HACVR Antibody; Anti-HAVCR Antibody; Anti-HAVCR-1 Antibody; Anti-KIM-1 Antibody; Anti-KIM1 Antibody; Anti-TIM Antibody; Anti-TIM-1 Antibody; Anti-TIM1 Antibody; Anti-TIMD-1 Antibody; Anti-TIMD1 Antibody

TIM-1 / KIM-1 背景情報

HAV cellular receptor 1 (HAVCR1), also known as Kidney injury molecule 1 (KIM-1) and T cell immunoglobulinmucin 1 (TIM-1), is a type â… integral membrane glycoprotein. KIM-1 protein is widely expressed with highest levels in kidney and testis. It has been shown to play a major role as a human susceptibility gene for asthma, allergy and autoimmunity. IgA1lambda is a specific ligand of KIM-1 protein and that their association has a synergistic effect in virus-receptor interactions. KIM-1 involves in the pathogenesis of acute kidney injury. It had been confirmed that KIM-1 is a human urinary renal dysfunction biomarker. Moreover, KIM-1 protein is a novel regulatory molecule of flow-induced calcium signaling.
hepatitis A virus cellular receptor 1
  • Tami C, et al. (2007) Immunoglobulin A (IgA) is a natural ligand of hepatitis A virus cellular receptor 1 (HAVCR1), and the association of IgA with HAVCR1 enhances virus-receptor interactions. J Virol. 81(7): 3437-46.
  • Rees AJ, et al. (2008) Kim-1/Tim-1: from biomarker to therapeutic target? Nephrol Dial Transplant. 23(11): 3394-6.
  • Chaturvedi S, et al. (2009) Assay validation for KIM-1: human urinary renal dysfunction biomarker. Int J Biol Sci. 5(2): 128-34.

Standard Antibody Development Service

Rabbit MAb

Mouse MAb

Rabbit PAb

Fast Antibody Development Service

Mouse MAb

Rabbit PAb

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