Anti-interferon-alpha / IFNA5 Antibody

Price:
Size:
Number:

Anti-interferon-alpha / IFNA5 Antibody (Rabbit Polyclonal 抗体) の製品情報

製品名
Anti-interferon-alpha / IFNA5 Antibody
検証済のアプリケーション
ELISA
交差反応
Reacts with: Human
特異性
Human interferon-alpha / IFNA5
免疫原
Recombinant Human IFNA5 / IFNaG protein (Catalog#10342-H08H)
調製
Produced in rabbits immunized with purified, recombinant Human IFNA5 / IFNaG (rh IFNA5 / IFNaG; Catalog#10342-H08H; P01569; Met1-Glu189). IFNA5 / IFNaG specific IgG was purified by Human IFNA5 / IFNaG affinity chromatography.
ソース
Polyclonal Rabbit IgG
精製
Protein A & Antigen Affinity
緩衝液
0.2 μm filtered solution in PBS
標識物
Unconjugated
状態
Liquid
配送方法
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
保存条件
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Anti-interferon-alpha / IFNA5 Antibody (Rabbit Polyclonal 抗体) 検証済のアプリケーション

アプリケーション 推奨希釈率/用量
ELISA 1:5000-1:10000
Please Note: Optimal concentrations/dilutions should be determined by the end user.

Anti-interferon-alpha / IFNA5 Antibody: 別名

Anti-IFN-alpha Antibody; Anti-IFN-alpha-5 Antibody; Anti-IFN-alphaG Antibody; Anti-INA5 Antibody; Anti-INFA5 Antibody; Anti-leIF G Antibody; Anti-RP11-380P16.5 Antibody

interferon-alpha / IFNA5 背景情報

Interferon, alpha 5 (IFNA5) belongs to the alpha/beta interferon family. IFNA5 is the only IFNA subtype detected in normal liver, while a mixture of subtypes is observed in the liver tissue of patients with chronic hepatitis C. Interferons are produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. IFN-alpha, the first cytokine to be produced by recombinant DNA technology, has emerged as an important regulator of growth and differentiation, affecting cellular communication and signal transduction pathways as well as immunological control. Originally discovered as an antiviral substance, the efficacy of IFN-alpha in malignant, viral, immunological, angiogenic, inflammatory, and fibrotic diseases suggests a spectrum of interrelated pathophysiologies. IFN-alpha emerged as a prototypic tumor suppressor protein that represses the clinical tumorigenic phenotype in some malignancies capable of differentiation.
完全な名称
interferon, alpha 5
参考文献
  • Lau JY, et al. (1993) Discrepancy between biochemical and virological responses to interferon-alpha in chronic hepatitis C. Lancet. 342(8881): 1208-9.
  • Kessler DS, et al. (1990) Interferon-alpha regulates nuclear translocation and DNA-binding affinity of ISGF3, a multimeric transcriptional activator. Genes Dev. 4(10): 1753-65.
  • Gutterman JU. Cytokine therapeutics: lessons from interferon alpha. Proc Natl Acad Sci U S A. 91(4): 1198-205.

Standard Antibody Development Service

Rabbit MAb

Mouse MAb

Rabbit PAb

Fast Antibody Development Service

Mouse MAb

Rabbit PAb

カートに追加しました カートに追加しませんでした カートを更新しています。少々お待ちください