Her2 / ERBB2 (タンパク質 | 抗体 | cDNA クローン | ELISA キット)

All Her2 / ERBB2 reagents are produced in house and quality controlled, including 35 Her2 / ERBB2 Antibody, 2 Her2 / ERBB2 ELISA, 39 Her2 / ERBB2 Gene, 2 Her2 / ERBB2 IP Kit, 17 Her2 / ERBB2 Lysate, 21 Her2 / ERBB2 Protein, 3 Her2 / ERBB2 qPCR. All Her2 / ERBB2 reagents are ready to use.

All Her2 / ERBB2 Reagents

Her2 / ERBB2 Protein (21)

Her2 / ERBB2 Antibody (35)

Her2 / ERBB2 ELISA キット(すぐに使用できます)& ELISA抗体ペアセット(すぐに使用できません)(2)

Her2 / ERBB2 cDNA Clone (39)

NM_004448.2

クローニングベクター cDNA 製品

In lentiviral vector

NM_001003817.1

クローニングベクター cDNA 製品

In lentiviral vector

BC061863.1

クローニングベクター cDNA 製品

In lentiviral vector

Her2 / ERBB2 Lysate (17)

Her2 / ERBB2 の背景知識

Epidermal growth factor receptor 2 (HER2), also known as ErbB2, NEU, and CD34, is a type I membrane glycoprotein, and belongs to the epidermal growth factor (EGF) receptor family. HER2 protein cannot bind growth factors due to the lacking of ligand binding domain of its own and autoinhibited constitutively. However, HER2 forms a heterodimer with other ligand-bound EGF receptor family members, therefore stabilizes ligand binding and enhances kinase-mediated activation of downstream molecules. HER2 plays a key role in development, cell proliferation and differentiation. HER2 gene has been reported to associate with malignancy and a poor prognosis in numerous carcinomas, including breast, prostate, ovarian, lung cancers and so on.

Her2 / ERBB2 の参考文献

  • Krawczyk N, et al. (2009) HER2 status on persistent disseminated tumor cells after adjuvant therapy may differ from initial HER2 status on primary tumor. Anticancer Res. 29(10): 4019-24.