HDAC2 (タンパク質 | 抗体 | cDNA クローン | ELISA キット)

All HDAC2 reagents are produced in house and quality controlled, including 1 HDAC2 Antibody, 2 HDAC2 Gene, 1 HDAC2 IP Kit, 1 HDAC2 qPCR. All HDAC2 reagents are ready to use.

HDAC2 の背景知識

HDAC2 gene product belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes, and are responsible for the deacetylation of lysine residues at the N-terminal regions of core histones (H2A, H2B, H3 and H4). This protein forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus, it plays an important role in transcriptional regulation, cell cycle progression and developmental events. Alternative splicing results in multiple transcript variants.

HDAC2 の参考文献

  • Hodge G, Jersmann H, Tran HB, et al. Lymphocyte senescence in COPD is associated with decreased histone deacetylase 2 expression by pro-inflammatory lymphocytes. Respiratory Research. 2015;16:130.