HDAC1 (タンパク質 | 抗体 | cDNA クローン | ELISA キット)

All HDAC1 reagents are produced in house and quality controlled, including 1 HDAC1 Antibody, 30 HDAC1 Gene, 1 HDAC1 qPCR. All HDAC1 reagents are ready to use.

HDAC1 の背景知識

Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. Histone Deacetylase 1 protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis.

HDAC1 の参考文献

  • Beharry AW, Sandesara PB, Roberts BM, Ferreira LF, Senf SM, Judge AR. HDAC1 activates FoxO and is both sufficient and required for skeletal muscle atrophy. Journal of Cell Science. 2014;127(7):1441-1453.