Anti-GFAP Antibody

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Anti-GFAP Antibody (Rabbit Polyclonal 抗体) の製品情報

製品名
Anti-GFAP Antibody
検証済のアプリケーション
WB,IHC-P
交差反応
Reacts with: Human
特異性
Human GFAP
免疫原
A synthetic peptide corresponding to the center region of the human GFAP
調製
Produced in rabbits immunized with A synthetic peptide corresponding to the center region of the human GFAP, and purified by antigen affinity chromatography.
ソース
Polyclonal Rabbit IgG
精製
Protein A & Antigen Affinity
緩衝液
0.2 μm filtered solution in PBS
標識物
Unconjugated
状態
Liquid
配送方法
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
保存条件
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Anti-GFAP Antibody (Rabbit Polyclonal 抗体) 検証済のアプリケーション

アプリケーション 推奨希釈率/用量
WB 1:500-1:1000
IHC-P 1:10000-1:50000
Please Note: Optimal concentrations/dilutions should be determined by the end user.

Anti-GFAP Antibody (Rabbit Polyclonal 抗体) の画像

Immunochemical staining of human GFAP in human brain with rabbit polyclonal antibody (1:25000, formalin-fixed paraffin embedded sections).

Anti-GFAP rabbit polyclonal antibody at 1:500 dilution

Lane A: Mouse brain Tissue Lysate

Lane B: Rat brain Tissue Lysate

Lysates/proteins at 30 μg per lane.

Secondary

Goat Anti-Rabbit IgG H&L (Dylight800) at 1/10000 dilution.

Developed using the Odyssey technique.

Performed under reducing conditions.

Predicted band size:50 kDa

Observed band size:42 kDa

Anti-GFAP Antibody: 別名

Anti-ALXDRD Antibody

GFAP 背景情報

GFAP is a cell-specific marker which belongs to the intermediate filament family. It can distinguish astrocytes from other glial cells during development. GFAP is expressed in cells lacking fibronectin. It is a type III intermediate filaments protein which contains three domains: the head, rod and tail domains. GFAP functions in many important entral nervous system (CNS) processes, including cell communication and the functioning of the blood brain barrier. Improper GFAP regulation can cause multiple disorders. Defects in GFAP is related to Alexander disease which is a rare disorder of the central nervous system. It is a progressive leukoencephalopathy whose hallmark is the widespread accumulation of Rosenthal fibers which are cytoplasmic inclusions in astrocytes.
完全な名称
glial fibrillary acidic protein
参考文献
  • Buniatian G, et al., 1998, Biology of the cell. 90(1): 53-61.
  • Chen YS, et al., 2011, Experimental Cell Research. 317(16): 2252-66.
  • Isaacs A, et al., 1998, Genomics. 51(1): 152-4.
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