CD200R (タンパク質 | 抗体 | cDNA クローン | ELISA キット)

All CD200R reagents are produced in house and quality controlled, including 18 CD200R Antibody, 1 CD200R ELISA, 28 CD200R Gene, 1 CD200R IP Kit, 5 CD200R Lysate, 5 CD200R Protein, 2 CD200R qPCR. All CD200R reagents are ready to use.

CD200R の背景知識

The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 32 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. Cell surface glycoprotein CD2 receptor 1 (CD2R1) is an isoform of CD2 receptors which is expressed on cells of the myeloid lineage. CD2R1 is a receptor for the OX-2 membrane glycoprotein. The receptor-substrate interaction may serve as a myeloid downregulatory signal.

CD200R の参考文献

  • Zola H, et al. (2007) CD molecules 2006-human cell differentiation molecules. J Immunol Methods. 318 (1-2): 1-5.
  • Ho IC, et al. (2009) GATA3 and the T-cell lineage: essential functions before and after T-helper-2-cell differentiation. Nat Rev Immunol. 9 (2): 125-35.
  • Matesanz-Isabel J, et al. (2011) New B-cell CD molecules. Immunology Letters.134 (2): 104-12.