ABCA1: ABCA1 Protein | ABCA1 Antibody

ABCA1 Gene family

ABCA1 Protein

ABCA1 protein function

cAMP-dependent and sulfonylurea-sensitive anion transporter. Key gatekeeper influencing intracellular cholesterol transport.

ABCA1 protein expression

Tissue specificity

Widely expressed, but most abundant in macrophages.

Induction

By bacterial lipopolysaccharides (LPS). LPS regulates expression through a liver X receptor (LXR) -independent mechanism. Repressed by ZNF202.

ABCA1 protein sequence

This sequence information is just for reference only.From Uniport

  • Length
    2,261.00
  • Mass (Da)
    254.00

ABCA1 Gene

ABCA1 cDNA / gene is a gene with protein product which located on 9q31.1. The ABCA1 gene is conserved in chimpanzee, dog, cow, mouse, rat, chicken, zebrafish, C.elegans, A.thaliana, and frog. 198 organisms have orthologs with human gene ABCA1.