AAMDC: AAMDC Protein | AAMDC Antibody

AAMDC Protein

AAMDC protein function

May play a role in preadipocyte differentiation and adipogenesis.

AAMDC protein sequence

This sequence information is just for reference only.From Uniport

  • Length
    122.00
  • Mass (Da)
    13.00

AAMDC Gene

The protein encoded by this gene is a protease inhibitor and cytokine transporter. It uses a bait-and-trap mechanism to inhibit a broad spectrum of proteases, including trypsin, thrombin and collagenase. It can also inhibit inflammatory cytokines, and it thus disrupts inflammatory cascades. Mutations in this gene are a cause of alpha-2-macroglobulin deficiency. This gene is implicated in Alzheimer's disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits. A related pseudogene, which is also located on the p arm of chromosome 12, has been identified. [NCBI]