A4GALT: A4GALT Protein | A4GALT Antibody

A4GALT Gene family

A4GALT Protein

A4GALT protein function

Necessary for the biosynthesis of the Pk antigen of blood histogroup P. Catalyzes the transfer of galactose to lactosylceramide and galactosylceramide. Necessary for the synthesis of the receptor for bacterial verotoxins.

A4GALT protein expression

Tissue specificity

Ubiquitous. Highly expressed in kidney, heart, spleen, liver, testis and placenta.

A4GALT protein sequence

This sequence information is just for reference only.From Uniport

  • Length
    353.00
  • Mass (Da)
    40.00

A4GALT Antibody

There are 1 A4GALT antibodies which are validated in multiple tissues with various applications, including WB. There are 1 A4GALT antibody for WB. Among all these A4GALT antibodies, there are 1 anti-A4GALT rabbit polyclonal antibodies . All the A4GALT anbodies are produced in house and all are in stock. A4GALT antibody customerized service is available.

A4GALT Gene

The protein encoded by this gene is a protease inhibitor and cytokine transporter. It uses a bait-and-trap mechanism to inhibit a broad spectrum of proteases, including trypsin, thrombin and collagenase. It can also inhibit inflammatory cytokines, and it thus disrupts inflammatory cascades. Mutations in this gene are a cause of alpha-2-macroglobulin deficiency. This gene is implicated in Alzheimer's disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits. A related pseudogene, which is also located on the p arm of chromosome 12, has been identified. [NCBI]