As of 18:00 on 23 April, the Ministry of Health (MOH) of Guinea has reported a cumulative total of 218 clinical cases of Ebola Virus Disease (EVD), including 141 deaths. To date, 191 patients have been tested for ebolavirus infection and 115 cases have been laboratory confirmed, including 72 deaths. In addition, 42 cases (34 deaths) meet the probable case definition for EVD and 61 cases (35 deaths) are classified as suspected cases. Twenty-six (26) health care workers (HCW) have been affected (18 confirmed), with 16 deaths (12 confirmed).
Clinical cases of EVD have been reported from Conakry (58 cases, including 24 deaths), Guekedou (127/91), Macenta (22/16), Kissidougou (6/5), Dabola (4/4) and Djingaraye (1/1). Laboratory confirmed cases and deaths have been reported from Conakry (37 cases, including 19 deaths), Guekedou (63/41), Macenta (13/10), Kissidougou (1/1) and Dabola (1/1). The date of onset of the most recent clinical case, a suspected case, is 23 April while the date of isolation of the most recent confirmed case is 22 April. Two new deaths have also been reported among existing cases; one of the deaths was a patient with confirmed EVD. Thirteen (13) patients are in isolation in Conakry (6 patients, 5 confirmed), Guekedou (7 patients, all confirmed). Contact tracing activities continue in all affected areas.
Overall, the epidemiological situation in Guinea has improved significantly over the last few weeks. The date of onset of the last reported case from Macenta was 24 days ago and a similar time has elapsed for Dabola (25 days), Kissigougou (26) and Djingaraye (31 days). Two incubation periods (42 days) without cases is the standard for declaring an EVD outbreak over in a particular location.
The Ministry of Health and Sanitation of Sierra Leone is currently investigating 3 patients with an illness compatible with a viral haemorrhagic fever (VHF) for EVD and Lassa fever (the latter is endemic in Sierra Leone). All rumours of EVD cases are being investigated and active case finding is also ongoing.
The laboratory at the Lassa Fever isolation facility at the Kenema Government Hospital is now analysing all suspected cases of VHF for both Lassa fever and EVD. As of 24 April 2014, 98 samples collected have been tested; 10 samples tested positive for Lassa fever and the remaining 88 tested negative for both diseases. Fifteen contacts have completed 21 days of follow up while 20 contacts remain under medical observation.
From 13 March, the date of onset of the first laboratory confirmed case in Liberia, to 24 April, the Ministry of Health and Social Welfare (MOHSW) of Liberia has reported a total of 35 clinically compatible cases of EVD; 6 confirmed cases, 2 probable cases and 27 suspected cases. The date of onset of the most recent confirmed case was 6 April. The MOHSW has started to reclassify suspected cases against their laboratory test results. Most of the suspected cases are expected to be discarded at the end of this process. (Article above quotes from WHO)