Text Size:AAA

14-3-3 sigma / Stratifin / YWHAS 抗体, ウサギポリクローナル抗体

    データシートレビュー関連製品プロトコル
    マウス SFN 抗体製品情報
    免疫原:Recombinant Mouse 14-3-3 sigma / Stratifin / YWHAS protein (Catalog#50576-MNCE)
    Clone ID:
    Ig タイプ:Rabbit IgG
    濃度:
    エンドトキシン:
    製剤:0.2 μm filtered solution in PBS
    調製:Produced in rabbits immunized with purified, recombinant Mouse 14-3-3 sigma / Stratifin / YWHAS (rh SFN; Catalog#50576-MNCE; NP_061224.2; Met1-Ser248). Total IgG was purified by Protein A affinity chromatography.
    Other SFN Antibody Products
    14-3-3 sigma/Stratifin/YWHAS 背景

    14-3-3 protein sigma (YWHAS), also known as stratifin (SFN) and epithelial cell marker protein 1, is a member of the14-3-3 proteins which are a family of conserved regulatory molecules expressed in all eukaryotic cells. The name 14-3-3 refers to the particular elution and migration pattern of these proteins on DEAE-cellulose chromatography and starch-gel electrophoresis. The 14-3-3 proteins eluted in the 14th fraction of bovine brain homogenate and were found on positions 3.3 of subsequent electrophoresis. There are seven genes that encode 14-3-3s in most mammals. 14-3-3 proteins have been identified as adapter proteins implicated in the regulation of a large spectrum of both general and specialized signaling pathway. More than 100 signaling proteins have been reported as 14-3-3 ligands including kinases, phosphatases, and transmembrane receptors, and the binding generally results in the modulation of the activity of the binding partner. YWHAE exists as a homodimer and present mainly in tissues enriched in stratified squamous keratinising epithelium. YWHAS has been repoted to interact with KRT17 and GAB2, and may regulate protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway upon binding to KRT17. Additionally, YWHAS (SFN) may also act as a p53-regulated inhibitor of G2/M progression.

    Product nameProduct name
    Size / Price
    カタログ: 50576-RP01-100
    定価: 
    価格:      (You Save: )

    Datasheet & Documentation

    All information of our products is subject to change without notice. Please refer to COA enclosed in shipped package for the newest information.
    注意:すべての製品は、"研究目的のみに使用するものであり、診断または治療目的に使用するものではありません"