OX40L cDNA ORF Clone in Cloning Vector, Mouse

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OX40L cDNA ORF Clone in Cloning Vector, Mouse: 製品情報

遺伝子
Mouse
NCBI 参考シーケンス番号
遺伝子の長さ
597 bp
シーケンスの特徴
Identical with the Gene Bank Ref. ID sequence except for the point mutations: 294C>T not causing the amino acid variation.
製品の特徴
Full length Clone DNA of Mouse tumor necrosis factor (ligand) superfamily, member 4.
プラスミド
ベクター
シークエンシングプライマー
SP6 and T7 or M13-47 and RV-M
品質管理
The plasmid is confirmed by full-length sequencing.
スクリーニング
細菌スクリーニング抵抗力
Ampicillin
保存 & 配送
配送方法
Each tube contains lyophilized plasmid.
保存条件
The lyophilized plasmid can be stored at ambient temperature for three months.

OX40L cDNA ORF ヌクレオチド配列およびアミノ酸配列に関する情報

**Sino Biological guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories.**

OX40L cDNA ORF Clone in Cloning Vector, Mouse: 別名

Ath-1 cDNA ORF Clone, Mouse; Ath1 cDNA ORF Clone, Mouse; CD134L cDNA ORF Clone, Mouse; gp34 cDNA ORF Clone, Mouse; OX-40L cDNA ORF Clone, Mouse; Ox40l cDNA ORF Clone, Mouse; TXGP1 cDNA ORF Clone, Mouse; Txgp1l cDNA ORF Clone, Mouse

OX40L 背景情報

OX-4L, also known as TNFSF4 and CD252, is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. OX-4L is an important costimulatory molecule that plays a crucial role in the regulation of T-cell-mediated immunity. The interaction of TNFSF4-TNFSF4 is involved in the pathogenesis of multiple autoimmune and inflammatory diseases such as systemic lupus erythematosus (SLE), carotid artery disease and cancer. OX-4L is a ligand for receptor TNFRSF4/OX4. It is found to play a role in T cell antigen-presenting cell (APC) interactions. In surface Ig- and CD4-stimulated B cells, this cytokine along with CD7 has been shown to provide CD28-independent costimulatory signals to T cells. This protein and its receptor are reported to directly mediate adhesion of activated T cells to vascular endothelial cells.
完全な名称
tumor necrosis factor (ligand) superfamily, member 4
参考文献
  • Lei W. et al., 2012, Ann Acad Med Singapore. 41 (5): 200-4.
  • Lee YH. et al., 2012, Hum Immunol. 73 (10): 1050-4.
  • Weiguang Y. et al., 2012, PLoS One. 7 (8): e41277.
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