LDOC1 cDNA ORF Clone in Cloning Vector, Rhesus

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LDOC1 cDNA ORF Clone in Cloning Vector, Rhesus: 製品情報

遺伝子
Rhesus
NCBI 参考シーケンス番号
遺伝子の長さ
441 bp
シーケンスの特徴
Identical with the Gene Bank Ref. ID sequence except for the point mutations: 204T/C not causing the amino acid variation. Please check the sequence information before order.
製品の特徴
Full length Clone DNA of Rhesus leucine zipper, down-regulated in cancer 1.
プラスミド
ベクター
シークエンシングプライマー
SP6 and T7 or M13-47 and RV-M
品質管理
The plasmid is confirmed by full-length sequencing.
スクリーニング
細菌スクリーニング抵抗力
Ampicillin
保存 & 配送
配送方法
Each tube contains lyophilized plasmid.
保存条件
The lyophilized plasmid can be stored at ambient temperature for three months.

LDOC1 cDNA ORF ヌクレオチド配列およびアミノ酸配列に関する情報

**Sino Biological guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories.**

LDOC1 背景情報

LDOC1 was first identified as a gene encoding a leucine zipper protein whose expression was decreased in a series of pancreatic and gastric cancer cell lines. LDOC1 gene is a known regulator of nuclear factor mediated pathway to apoptosis through inhibition of nuclear factor kappa B (NF-kappaB). Upregulation of LDOC1 in HIBEC increases the expression of NF-kappaB, which may promote the activation of IL-2 and TNF-alpha secretion and inhibit cell apoptosis. The silencing of LDOC1 is a frequent event in cervical cancer and may be of interest as a molecular marker in cervical cancer.
完全な名称
leucine zipper, down-regulated in cancer 1
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