Endogenous ligands

Approved Symbol Approved Name Synonyms Protein & antibody reagent
ADCYAP1 ADCYAP1 PACAP, pituitary adenylate cyclase activating polypeptide, prepro-PACAP
Adiponectin ADIPOQ ACRP30, adiponectin, adiponectin precursor, AdipoQ, adipose most abundant gene transcript 1, apM1, GBP28
Adrenomedullin ADM AM
ADM2 ADM2 AM2, FLJ21135
AGRP AGRP Agrt, ART, ASIP2
Angiotensinogen AGT alpha-1 antiproteinase, antitrypsin
AMH AMH MIS
Annexin A1/ANXA1 ANXA1
APLN APLN apelin, XNPEP2
APP / Protease nexin-II APP peptidase nexin-II
Amphiregulin AREG
ARF1 ARF1
D4 GDI/ARHGDIB ARHGDIB Ly-GDI, RhoGDI2
AVP AVP ADH, antidiuretic hormone, copeptin, diabetes insipidus, neurohypophyseal, neurophysin II, prepro-arginine-vasopressin-neurophysin II, prepro-AVP-NP II
BID BID
BMP10 BMP10
BMP-2 BMP2
BMP4 BMP4
BMP5 BMP5
BMP6 BMP6 VGR1
BMP7 BMP7 OP-1, osteogenic protein 1
BMP8A BMP8A
BMP8B BMP8B OP-2, osteogenic protein 2
Complement component 3 C3 ARMD9, C3a, C3a anaphylatoxin, C3b, complement component C3a, complement component C3b, CPAMD1, prepro-C3
C5a C5 C5a, C5a anaphylatoxin, C5b, CPAMD4, prepro-C5
Procalcitonin / CALCA CALCA calcitonin
CALCB CALCB CGRP-II, FLJ30166
Calmodulin 1/CALM1 CALM1 CAMI, DD132, PHKD, phosphorylase kinase subunit delta, prepro-calmodulin 1
CALM2 CALM2 CAMII, PHKD, phosphorylase kinase subunit delta, prepro-calmodulin 2
calmodulin 3/CALM3 CALM3 PHKD, phosphorylase kinase subunit delta, prepro-calmodulin 3
Cathelicidin/CAP-18/Fall-39 CAMP CAP18, FALL39, FALL-39, LL37
CCK Cck cholecystokinin triacontatriapeptide, prepro-cholecystokinin
I-309 CCL1 I-309, inflammatory cytokine I-309, P500, SISe, T lymphocyte-secreted protein I-309, TCA3
Eotaxin / CCL11 CCL11 eotaxin, eotaxin-1, MGC22554
MCP-4 CCL13 CKb10, MCP-4, MGC17134, NCC-1, SCYL1
CCL14 CCL14 CKb1, HCC-1, HCC-3, MCIF, NCC-2, SCYL2
MIP-5 CCL15 CC chemokine 3, chemokine CC-2, HCC-2, HMRP-2B, leukotactin 1, Lkn-1, macrophage inflammatory protein 5, MIP-1 delta, MIP-1d, MIP-5, NCC-3, SCYL3
LEC / CCL16 CCL16 CKb12, HCC-4, LCC-1, LEC, LMC, Mtn-1, NCC-4, SCYL4
TARC CCL17 ABCD-2, TARC
CCL19/MIP-3b CCL19 beta chemokine exodus-3, CC chemokine ligand 19, CK beta-11, CKb11, EBI1-ligand chemokine, ELC, exodus-3, macrophage inflammatory protein 3-beta, MIP-3b
MCP-1 / CCL2 CCL2 GDCF-2, HC11, MCAF, MCP1, MCP-1, MGC9434, monocyte chemoattractant protein-1, monocyte chemotactic and activating factor, monocyte chemotactic protein 1, homologous to mouse Sig-je, monocyte secretory protein JE, small inducible cytokine subfamily A (Cys-Cys), member 2, SMC-CF
CCL20 CCL20 CKb4, exodus-1, LARC, MIP-3a, ST38
CCL21 CCL21 6Ckine, beta chemokine exodus-2, CKb9, ECL, Efficient Chemoattractant for Lymphocytes, exodus-2, secondary lymphoid tissue chemokine, SLC, TCA4
MDC CCL22 A-152E5.1, ABCD-1, DC/B-CK, MDC, MGC34554, STCP-1
MPIF-1 / CCL23 CCL23 CKb8, Ckb-8, MIP-3, MPIF-1
Eotaxin-2 CCL24 Ckb-6, CK-beta-6, eotaxin-2, eotaxin-2, MPIF2, MPIF-2, myeloid progenitor inhibitory factor 2
CCL25/TECK CCL25 Ck beta-15, Ckb15, TECK, TECKvar, thymus expressed chemokine
CCL26/Eotaxin-3 CCL26 CC chemokine IMAC, chemokine N1, eotaxin-3, eotaxin-3, IMAC, macrophage inflammatory protein 4-alpha, MIP-4a, MIP-4alpha, small inducible cytokine A26, thymic stroma chemokine-1, TSC-1
CCL27 CCL27 ALP, CC chemokine ILC, CTACK, CTAK, cutaneous T-cell attracting chemokine, ESkine, IL-11 Ralpha-locus chemokine, ILC, PESKY, skinkine
CCL28 CCL28 CC chemokine CCL28, CCK1, MEC, mucosae-associated epithelial chemokine, SCYA28, small inducible cytokine A28, small inducible cytokine subfamily A (Cys-Cys), member 28
MIP-1 alpha / CCL3 CCL3 G0S19-1, LD78ALPHA, MIP-1-alpha
CCL4 CCL4 Act-2, AT744.1, MIP-1-beta
CCL5 CCL5 beta-chemokine RANTES, MGC17164, RANTES, regulated upon activation, normally T-expressed, and presumably secreted, SISd, SIS-delta, small inducible cytokine subfamily A (Cys-Cys), member 5, T-cell specific protein p288, T-cell specific RANTES protein, TCP228
MCP3 CCL7 FIC, MARC, MCP3, MCP-3, monocyte chemoattractant protein 3, monocyte chemotactic protein 3, NC28
MCP2 CCL8 HC14, MCP-2
PD-L1 CD274 B7 homolog 1, B7-H, B7H1, B7-H1, PDL1, PD-L1
CD40 Ligand CD40LG CD154, CD40 antigen ligand, CD40L, gp39, hCD40L, hyper-IgM syndrome, T-B cell-activating molecule, TNF-related activation protein, TRAP, tumor necrosis factor (ligand) superfamily member 5
c-FLIP/FLIP CFLAR CASH, Casper, c-FLIP, CLARP, FLAME, FLIP, I-FLICE, MRIT
Chorionic Gonadotropin / CGA CGA chorionic gonadotropin, alpha polypeptide, follicle-stimulating hormone alpha subunit, FSHA, glycoprotein hormones alpha chain, GPHa, GPHA1, HCG, LHA, luteinizing hormone alpha chain, lutropin alpha chain, thyroid-stimulating hormone alpha chain, TSHA
CGB3 CGB3
Contactin-1 CNTN1 F3, glycoprotein gP135, GP135
alpha COP I COPA HEP-COP, proxenin, xenin
Cortistatin CORT MGC32686, prepro-cortistatin
CRH CRH corticoliberin, corticotropin-releasing factor, CRF, CRH1
G-CSF CSF3 filgrastim, granulocyte colony stimulating factor, lenograstim, MGC45931, pluripoietin
Cathepsin G / CTSG CTSG CG
Fractalkine CX3CL1 ABCD-3, C3Xkine, CXC3, CXC3C, fractalkine, neurotactin, NTN
CXCL1 CXCL1 GROa, melanoma growth stimulating activity, alpha, MGSA-a, NAP-3, SCYB1
IP-10/CXCL10 CXCL10 C7, crg-2, gIP-10, IFI10, IP-10, mob-1
CXCL11 CXCL11 b-R1, H174, IP-9, I-TAC
SDF-1 CXCL12 PBSF, SCYB12, SDF-1a, SDF-1b, TLSF-a, TLSF-b, TPAR1
BCA-1 CXCL13 ANGIE, ANGIE2, BCA-1, B-cell chemoattractant, BLC, BLR1L
CXCL16 CXCL16 CXC chemokine ligand 16, CXCLG16, SRPSOX, SR-PSOX
GRO Beta / CXCL2 CXCL2 CINC-2a, GROb, MGSA-b, MIP-2a, SCYB2
GRO gamma CXCL3 CINC-2b, GROg, MIP-2b, SCYB3
CXCL5 CXCL5 ENA-78
CXCL6 / GCP-2 CXCL6 CKA-3, GCP-2, granulocyte chemotactic protein 2
IL-8 CXCL8 3-10C, alveolar macrophage chemotactic factor I, AMCF-I, b-ENAP, beta endothelial cell-derived neutrophil activating peptide, GCP1, GCP-1, granulocyte chemotactic protein 1, IL-8, K60, LECT, LUCT, lung giant cell carcinoma-derived chemotactic protein, lymphocyte derived neutrophil activating peptide, LYNAP, MDNCF, MONAP, monocyte-derived neutrophil chemotactic factor, monocyte-derived neutrophil-activating peptide, NAF, NAP1, NAP-1, neutrophil-activating peptide 1, SCYB8, TSG-1, tumor necrosis factor-induced gene 1
CXCL9 CXCL9 crg-10, Humig, SCYB9
DEFB4A DEFB4A beta defensin 2, beta defensin-2, beta-defensin 2, DEFB-2, HBD-2, SAP1
Endothelin 1 EDN1 ET1
Endothelin 2 EDN2 ET2
Endothelin 3 EDN3 ET3
Erythropoietin EPO EP
Thrombin / Coagulation Factor II F2 prepro-coagulation factor II
Fas Ligand FASLG CD178, FasL
Fibrinogen FGA
Fibrinopeptide B FGB
FGF1 FGF1 AFGF, ECGF, ECGFA, ECGFB, ECGF-beta, endothelial cell growth factor, alpha, endothelial cell growth factor, beta, FGF-alpha, GLIO703, HBGF1, heparin-binding growth factor 1
FGF2 FGF2
FGF4 FGF4 HBGF-4, HST, HST-1, human stomach cancer, transforming factor from FGF-related oncogene, kaposi sarcoma oncogene, KFGF, K-FGF, transforming protein KS3
FGF5 FGF5
FGF6 FGF6
KGF FGF7 keratinocyte growth factor, KGF
FGF8 Fgf8 AIGF, androgen-induced growth factor
FGF9 FGF9 glia-activating factor
Fibrinogen gamma chain / FGG FGG
Flt3 Ligand FLT3LG
Fibronectin FN1 CIG, cold-insoluble globulin, FINC, GFND2, LETS, migration-stimulating factor, MSF
FSH Beta FSHB follitropin, beta chain
Galanin GAL galanin-message-associated peptide, GAL-GMAP, GLNN, GMAP
GALP GALP
GAST/Gastrin GAST preprogastrin
GCG/Glucagon GCG glicentin-related polypeptide, GLP1, GLP-1, GLP2, glucagon-like peptide 1, glucagon-like peptide 2, GRPP, preproglucagon
GDF-1 GDF1
GDF10 GDF10 BMP-3b
GDF-2/BMP-9 GDF2 BMP9, BMP-9
GDF3 GDF3
GDF-9 GDF9
Growth Hormone GH1 GH, GHN, GH-N, hGH-N, pituitary growth hormone, somatotropin
GH2/Growth hormone 2 GH2 GHL, GHV, GH-V, hGH-V, placental-specific growth hormone, placenta-specific growth hormone
GHRH GHRH sermorelin, somatocrinin, somatoliberin
GHRL GHRL ghrelin, MTLRP, obestatin, prepro-appetite regulatory hormone
GIP GIP glucose-dependent insulinotropic polypeptide
GNRH1 GNRH1 progonadoliberin-1
GNRH2 GNRH2 progonadoliberin-2
GRP/Gastrin-releasing peptide GRP bombesin, neuromedin C, prepro-GRP
GUCA2A GUCA2A prepro-guanylin, STARA
GUCA2B GUCA2B prepro-uroguanylin
HCRT HCRT orexin, OX, PPOX, prepro-orexin
HEBP1 HEBP1 HBP, HEBP
IAPP/Amylin IAPP amylin, AMYLIN, DAP, IAP
ICAM-1 ICAM1 BB2, CD54, human rhinovirus receptor
ICAM-2 ICAM2 CD102
ICOS ligand ICOSLG B7 homolog 2, B7 homologue 2, B7H2, B7-H2, B7-related protein 1, B7RP1, B7RP-1, CD275, GL50, ICOS-L, KIAA0653
IGF1 IGF1 IGF, IGF1A, IGFI, IGF-I, somatomedin C
IL11 IL11 adipogenesis inhibitory factor, AGIF, IL-11, oprelvekin
IL-1 alpha / IL1A IL1A hematopoietin-1, IL-1A, IL1-ALPHA, IL1F1, preinterleukin 1 alpha, pro-interleukin-1-alpha
IL-1 beta IL1B IL-1B, IL1-BETA, IL1F2
IL1RA IL1RN ICIL-1RA, IL1F3, IL1RA, IL-1RN, interleukin-1 receptor antagonist protein, intracellular interleukin-1 receptor antagonist, IRAP, MGC10430
Inhibin beta A / Activin A INHBA
Inhibin beta B INHBB
Insulin INS
INSL3 INSL3 MGC119818, MGC119819, prepro-INSL3, RLF
INSL5 INSL5 prepro-INSL5
KISS1 KISS1 kisspeptin, prepro-kisspeptin
Kininogen 1 KNG1 alpha-2-thiol proteinase inhibitor, BK, bradykinin
Galectin-1 LGALS1 GBP
Galectin 3 / LGALS3 LGALS3 advanced glycation end-product receptor 3, GALIG, MAC-2
LGALS3BP LGALS3BP 90K, BTBD17B, CyCAP, gp90, L3 antigen, M2BP, Mac-2-binding protein, MAC-2-BP, serum protein 90K, TANGO10B, transport and golgi organization 10 homolog B (Drosophila)
LHB LHB CGB4, hLHB, interstitial cell stimulating hormone, beta chain, LSH-B, luteinizing hormone beta subunit, lutropin, beta chain
LIF LIF CDF, cholinergic differentiation factor, DIA, differentiation inhibitory activity, differentiation-inducing factor, hepatocyte-stimulating factor III, HILDA, human interleukin in DA cells
LRRC4B LRRC4B DKFZp761A179, HSM, netrin-G3 ligand
Motilin MLN prepromotilin
MMP1 MMP1 interstitial collagenase
MMP13 MMP13 CLG3, collagenase 3
NCAN NCAN neurocan proteoglycan
B7-H6 NCR3LG1 B7 homolog 6, B7-H6, DKFZp686O24166
NDP/EVR2 NDP norrin
NMS NMS prepro-NMS
NMU NMU prepro-NMU
NPB NPB PPL7, PPNPB, prepro-NPB
NPFF NPFF FMRFAL
NPPA NPPA
NPPB NPPB
NPPC NPPC CNP
NPS NPS prepro-neuropeptide S
NPVF NPVF FMRFamide-related peptide precursor, RFamide-related peptide precursor, RFRP
NPW NPW PPL8, prepro-neuropeptide W
Neuropeptide Y NPY prepro-neuropeptide Y, PYY4
Neurotensin NTS neuromedin N, pro-neurotensin/neuromedin
OXT OXT neurophysin I, OT-NPI, OXT-NPI, oxytocin
PD-L2 PDCD1LG2 B7 dendritic cell molecule, B7-DC, bA574F11.2, Btdc, CD273, PDL2, PD-L2
PDYN/ProDynorphin PDYN ADCA, beta-neoendorphin, dynorphin, leu-enkephalin, leumorphin, neoendorphin-dynorphin-enkephalin prepropeptide, PENKB, preproenkephalin B, rimorphin
PENK/proenkephalin PENK preproenkephalin
PMCH PMCH MCH
PNOC PNOC N/OFQ, nocistatin, NOP, orphanin FQ, PPNOC
POMC POMC ACTH, adrenocorticotropic hormone, adrenocorticotropin, alpha-melanocyte stimulating hormone, beta-endorphin, beta-lipotropin, beta-melanocyte stimulating hormone, CLIP, LPH, MSH, NPP, opiomelanocortin prepropeptide, POC
CXCL7 PPBP Beta-TG, beta-thromboglobulin, b-TG1, chemokine (C-X-C motif) ligand 7, connective tissue-activating peptide III, CTAP3, CTAPIII, CXCL7, LA-PF4, LDGF, MDGF, NAP-2, NAP-2-L1, neutrophil-activating peptide-2, PBP, platelet basic protein, SCYB7, TGB, TGB1
PPY PPY pancreatic polypeptide Y, PNP, prepro-PP (prepropancreatic polypeptide)
PRLH PRLH PRH
Protein C PROC prepro-protein C
Prokineticin 1 / EG-VEGF PROK1 black mamba toxin-related protein, EGVEGF, mambakine, PK1, PRK1
PROK2 PROK2 BV8, KAL4, MIT1, PK2, protein Bv8 homolog
PSAP / Prosaposin PSAP variant Gaucher disease and variant metachromatic leukodystrophy
PTH / Parathyroid Hormone PTH parathormone, parathyrin, parathyroid hormone 1, preproparathyroid hormone, prepro-PTH, PTH1
PTH2 PTH2 TIP39, tuberoinfundibular 39 residues
PTHLH PTHLH HHM, osteostatin, parathyroid hormone-like hormone preproprotein, parathyroid hormone-related protein preproprotein, PLP, PTHR, PTHRP
Pleiotrophin PTN HBGF8, HBNF, heparin binding growth factor 8
PYY PYY prepro-PYY, PYY1
QRFP QRFP 26RFa, P518, prepro-QRFP
Rac1 RAC1 p21-Rac1, Rac-1, TC-25
RAC2 RAC2 EN-7
RAC3 RAC3
Chemerin / RARRES2 RARRES2 chemerin, HP10433, TIG2
RB1/OSRC RB1 PPP1R130, prepro-retinoblastoma-associated protein, protein phosphatase 1, regulatory subunit 130, RB
RGS2 RGS2
Relaxin 1 / RLN1 RLN1 H1, prorelaxin H1
Relaxin-2/RLN2 RLN2 bA12D24.1.1, bA12D24.1.2, H2, prorelaxin H2, relaxin H2, relaxin, ovarian, of pregnancy, RLXH2
RLN3 RLN3 H3, prorelaxin H3, RXN3, ZINS4
RSPO1 RSPO1 FLJ40906, RSPONDIN
RSPO2 RSPO2 MGC35555
RSPO3 RSPO3 FLJ14440
RSPO4 RSPO4 dJ824F16.3
SAA1 SAA1 PIG4, TP53I4
SCT SCT prepro-secretin
PSGL-1 / CD162 SELPLG CD162, PSGL-1
Osteopontin Spp1 BSPI, early T-lymphocyte activation 1, ETA-1
Somatostatin / SST SST prepro-somatostatin, SMST, somatostatin-14, somatostatin-28
Tac1 Tac1 neurokinin 1, neurokinin 2, neurokinin alpha, neuromedin L, neuropeptide gamma, neuropeptide K, NPK, preprotachykinin, protachykinin, substance K, substance P
TAC3 TAC3 NKB, preprotachykinin-B, ZNEUROK1
TAC4 TAC4 hemokinin, HK-1, Pptc, PPT-C
TGF beta 1 TGFB1 Camurati-Engelmann disease, CED, prepro-transforming growth factor beta-1, TGFbeta
TGF beta 2 TGFB2 prepro-transforming growth factor beta-2
TGF-beta 3/TGFB3 TGFB3 prepro-transforming growth factor beta-3
Thrombopoietin THPO c-mpl ligand, megakaryocyte colony-stimulating factor, megakaryocyte growth and development factor, megakaryocyte stimulating factor, MPL ligand, MPLLG, myeloproliferative leukemia virus oncogene ligand, prepro-thrombopoietin, thrombopoietin nirs variant 1, TPO
TRH TRH prothyroliberin
TSHB TSHB
UCN UCN prepro-urocortin, UI, UROC
UCN2 UCN2 prepro-urocortin 2, SRP, UCNI, UCN-II, URP
UCN3 UCN3 prepro-urocortin 3, SPC, stresscopin, UCNIII
UTS2 UTS2 prepro U-II, PRO1068, UCN2, UII, U-II
UTS2B UTS2B prepro-URP, U2B, URP
VCAM1 VCAM1 CD106
VIP VIP prepro-VIP
Vitronectin VTN complement S-protein, serum spreading factor, somatomedin B, VN
Von Willebrand Factor / vWF vWF
Wnt-1 WNT1
Wnt2 Wnt2 IRP, secreted growth factor
Wnt3 Wnt3 MGC131950, MGC138321, MGC138323, WNT-3 proto-oncogene protein
WNT3A WNT3A
Wnt4 Wnt4 WNT-4
Wnt5a Wnt5a hWNT5A, WNT-5A protein
Wnt7b Wnt7b
Lymphotactin / XCL1 XCL1 ATAC, LPTN, lymphotactin, SCM-1, SCM-1a
XCL2 XCL2 SCM-1b