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マウス Calnexin / CANX Gene ORF cDNA clone in cloning vector

データシートレビュープロトコル
発現宿主: Human Cells  
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13929-H02H-20
13929-H02H-100
20 µg 
100 µg 
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発現宿主: Human Cells  
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53126-M08H-20
53126-M08H-100
20 µg 
100 µg 
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反応度: Human  
アプリケーション: WB  
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102109-T32-50
102109-T32-200
102109-T32-100
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200 µg 
100 µg 
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Calnexin / CANX  cdna-clone 背景

Calnexin is a calcium-binding protein that belongs to the calreticulin family. It interacts with newly synthesized glycoproteins in the endoplasmic reticulum. Calnexin seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. Associated with partial T-cell antigen receptor complexes that escape the ER of immature thymocytes, it may function as a signaling complex regulating thymocyte maturation. Additionally it may play a role in receptor-mediated endocytosis at the synapse.

マウス Calnexin / CANX  cdna-clone 参考文献
  • Rajagopalan S, et al. (1994) Retention of unassembled components of integral membrane proteins by Calnexin(CANX). Science. 263(5145):387-90.
  • Lenter M, et al. (1994) The integrin chains beta 1 and alpha 6 associate with the chaperone Calnexin(CANX) prior to integrin assembly. J Biol Chem. 269(16):12263-8.
  • Pind S, et al. (1994) Retention of unassembled components of integral membrane proteins by Calnexin(CANX). Science. 263(5145):387-90.
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