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FABP4 / ALBP / A-FABP 抗体, ウサギモノクローナル抗体

データシートレビュープロトコル
発現宿主: E. coli  
  • Slide 1
12109-H07E-50
12109-H07E-100
50 µg 
100 µg 
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発現宿主: E. coli  
  • Slide 1
50652-M08E-50
50652-M08E-100
50 µg 
100 µg 
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発現宿主: E. coli  
  • Slide 1
50652-M07E-20
50652-M07E-100
20 µg 
100 µg 
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発現宿主: Human Cells  
  • Slide 1
50652-M35H-20
50652-M35H-100
20 µg 
100 µg 
Add to Cart
発現宿主: Human Cells  
  • Slide 1
50652-M08H-50
50652-M08H-100
50 µg 
100 µg 
Add to Cart

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FABP4 /A-FABP antibody 背景

Fatty acid-binding protein, adipocyte, also known as Adipocyte-type fatty acid-binding protein, Fatty acid-binding protein 4, Adipocyte lipid-binding protein, and FABP4, is a cytoplasm protein which belongs to the calycin superfamily and Fatty-acid binding protein (FABP) family. In familial combined hyperlipidemia (FCHL), FABP4 correlated to body mass index (BMI), waist circumference and homeostasis model assessment (HOMA) index.FABP4 levels were associated with triglyceride-rich lipoproteins. In humans serum FABP4 levels correlate significantly with features of PCOS. It appears to be a determinant of atherogenic dyslipidemia. FABP4 pathway mediates the sebaceous gland hyperplasia in keratinocyte-specific Pten-null mice. FABP4 concentration significantly increased with an increasing of MS features and was strongly correlated with body-mass index, triglycerides, HDL-cholesterol concentrations and blood pressure. Patients in the highest quartile of FABP4 presented a six-fold increased odds ratio for MS and a three-fold increased odds for LD, adjusted by age, sex, body-mass index and the antiretroviral therapy. FABP4 is a strong plasma marker of metabolic disturbances in HIV-infected patients, and therefore, could serve to guide therapeutic intervention in this group of patients.

人々 FABP4 /A-FABP antibody 参考文献
  • van Dongen,M.J. et al., 2002, J Am Chem Soc. 124 (40): 11874-80.
  • Coll, B. et al., 2008, Atherosclerosis  199 (1):147-53.
  • Hoashi,S. et al., 2008, BMC Genet. 9 :84.
  • Cai,H. et al., 2010, Bioorg Med Chem Lett  20 (12):3675-9.
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