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LFA-3 / CD58 抗体, ウサギポリクローナル抗体, Antigen Affinity Purified

データシートレビュープロトコル
発現宿主: Human Cells  
  • Slide 1
12409-H08H-50
12409-H08H-100
50 µg 
100 µg 
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発現宿主: Human Cells  
  • Slide 1
12409-H02H-50
12409-H02H-100
50 µg 
100 µg 
Add to Cart
発現宿主: Human Cells  
  • Slide 1
90190-C08H-50
90190-C08H-100
50 µg 
100 µg 
Add to Cart

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LFA-3 / CD58 antibody 背景

CD53 is a member of the transmembrane 4 superfamily, also called the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. These proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. CD53 is a cell surface glycoprotein that is known to complex with integrins. Familial deficiency of CD53 gene has been linked to an immunodeficiency associated with recurrent infectious diseases caused by bacteria, fungi and viruses. CD53 contributes to the transduction of CD2-generated signals in T cells and natural killer cells and has been suggested to play a role in growth regulation.

Immune Checkpoint   Immunotherapy   Cancer Immunotherapy   Targeted Therapy

人々 LFA-3 / CD58 antibody 参考文献
  • Rochelle JM. et al., 1993, Int Immunol. 5 (2): 209-16.
  • Virtaneva KI. et al., 1993, Immunogenetics. 37 (6): 461-5.
  • Horejsí V. et al., 1991, FEBS Lett. 288 (1-2): 1-4.
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