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IFNGR1 / CD119 抗体, ウサギポリクローナル抗体, Antigen Affinity Purified

データシートレビュープロトコル
発現宿主: Human Cells  
  • Slide 1
10338-H08H-200
10338-H08H-100
200 µg 
100 µg 
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発現宿主: Human Cells  
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10338-H03H-200
10338-H03H-100
200 µg 
100 µg 
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発現宿主: Human Cells  
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50705-M02H-200
50705-M02H-100
200 µg 
100 µg 
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発現宿主: Human Cells  
  • Slide 1
50705-M08H-200
50705-M08H-100
200 µg 
100 µg 
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発現宿主: Human Cells  
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80182-R02H-50
80182-R02H-100
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100 µg 
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発現宿主: Human Cells  
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90207-C02H-200
90207-C02H-100
200 µg 
100 µg 
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発現宿主: Human Cells  
  • Slide 1
90207-C08H-50
90207-C08H-100
50 µg 
100 µg 
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IFNGR1/CD119 antibody 背景

The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD119 (cluster of differentiation 119), also known as IFNGR1 ( interferon gamma receptor 1), is part of the heterodimeric gamma interferon receptor which consists of IFNGR1 (CD119) and IFNGR2. The IFNGR1 gene encodes the ligand-binding chain (alpha) of the interteron receptor while IFNGR gene encodes the non-ligand binding partner. The ability of the interferon-γ was achieved through binding to the interferon receptor CD119. After binding, the products of activated T-lymphocytes interferon-γ exerts antiviral activity, growth inhibitory effect, and several immune- regulatory activities on a variety of cell types.

マウス IFNGR1/CD119 antibody 参考文献
  • Zola H, et al. (2007) CD molecules 2006-human cell differentiation molecules. J Immunol Methods. 318 (1-2): 1-5.
  • Ho IC, et al. (2009) GATA3 and the T-cell lineage: essential functions before and after T-helper-2-cell differentiation. Nat Rev Immunol. 9 (2): 125-35.
  • Matesanz-Isabel J, et al. (2011) New B-cell CD molecules. Immunology Letters.134 (2): 104-12
  • Novick D, et al. (1987) The human interferon-gamma receptor. The journal of biological chemistry. 262 (18): 8483-7
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