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インフルエンザ A H5N8 (A/breeder duck/Korea/Gochang1/2014 (Gochang1)) Neuraminidase / NA (Codon Optimized) ORF mammalian expression plasmid, N-Flag タグ

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発現宿主: Human Cells  
    11058-VNAHC-200
    11058-VNAHC-100
    200 U 
    100 U 
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    製品の説明:   
    発現宿主: Baculovirus-Insect Cells  
    • Slide 1
    11058-V07B-50
    11058-V07B-5
    11058-V07B-20
    11058-V07B-10
    50 µg 
    5 µg 
    20 µg 
    10 µg 
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    発現宿主: Human Cells  
    • Slide 1
    40197-V07H-50
    40197-V07H-100
    50 µg 
    100 µg 
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    製品の説明: Active  
    発現宿主: Human Cells  
      11058-VNAHC1-200
      200 U 
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      製品の説明: Active  
      発現宿主: Human Cells  
        11058-VNAHC2-800
        800 U 
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        製品の説明: Active  
        発現宿主: Human Cells  
        • Slide 1
        11058-V01H-50
        11058-V01H-100
        11058-V01H-10
        50 µg 
        100 µg 
        10 µg 
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        製品の説明: Active  
        発現宿主: Human Cells  
          40017-VNAHC-800
          800 U 
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          製品の説明: Active  
          発現宿主: Human Cells  
            40017-VNAHC2-80
            40017-VNAHC2-500
            80 U 
            500 U 
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            発現宿主: Human Cells  
            • Slide 1
            40199-V07H-50
            40199-V07H-100
            40199-V07H-10
            50 µg 
            100 µg 
            10 µg 
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            製品の説明: Active  
            発現宿主: Human Cells  
              40017-VNAHC4-1000
              1000 U 
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              製品の説明: Active  
              発現宿主: Human Cells  
                40017-VNAHC1-600
                40017-VNAHC1-400
                600 U 
                400 U 
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                発現宿主: Human Cells  
                • Slide 1
                40017-V07H-50
                40017-V07H-20
                40017-V07H-10
                50 µg 
                20 µg 
                10 µg 
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                製品の説明: Active  
                発現宿主: Human Cells  
                  40017-VNAHC3-50
                  50 U 
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                  発現宿主: Human Cells  
                    40235-VNAHC-1500
                    40235-VNAHC-100
                    1500 U 
                    100 U 
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                    製品の説明:   
                    発現宿主: Baculovirus-Insect Cells  
                    • Slide 1
                    40235-V07B-50
                    40235-V07B-100
                    50 µg 
                    100 µg 
                    Add to Cart
                    発現宿主: Human Cells  
                    • Slide 1
                    40064-V07H-B-50
                    40064-V07H-B-100
                    40064-V07H-B-10
                    50 µg 
                    100 µg 
                    10 µg 
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                    製品の説明: Active  
                    発現宿主: Human Cells  
                      11676-VNAHC-800
                      11676-VNAHC-60
                      800 U 
                      60 U 
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                      製品の説明:   
                      発現宿主: Human Cells  
                      • Slide 1
                      40018-V07H-50
                      40018-V07H-20
                      40018-V07H-10
                      50 µg 
                      20 µg 
                      10 µg 
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                      製品の説明: Active  
                      発現宿主: Human Cells  
                        11676-VNAHC1-60
                        11676-VNAHC1-300
                        60 U 
                        300 U 
                        Add to Cart
                        発現宿主: Human Cells  
                        • Slide 1
                        40064-V07H-50
                        40064-V07H-100
                        40064-V07H-10
                        50 µg 
                        100 µg 
                        10 µg 
                        Add to Cart
                        発現宿主: Human Cells  
                        • Slide 1
                        40202-V07H-50
                        40202-V07H-100
                        50 µg 
                        100 µg 
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                        発現宿主: Human Cells  
                          40202-VNAHC-1000
                          40202-VNAHC-100
                          1000 U 
                          100 U 
                          Add to Cart
                          製品の説明: Active  
                          発現宿主: Human Cells  
                            40109-VNAHC-20
                            20 U 
                            Add to Cart
                            発現宿主: Human Cells  
                            • Slide 1
                            40109-V07H-50
                            40109-V07H-100
                            40109-V07H-10
                            50 µg 
                            100 µg 
                            10 µg 
                            Add to Cart
                            製品の説明: Active  
                            発現宿主: Human Cells  
                              40108-VNAHC-1500
                              40108-VNAHC-100
                              1500 U 
                              100 U 
                              Add to Cart
                              製品の説明:   
                              発現宿主: Human Cells  
                              • Slide 1
                              40108-V07H-50
                              40108-V07H-100
                              40108-V07H-10
                              50 µg 
                              100 µg 
                              10 µg 
                              Add to Cart
                              発現宿主: Human Cells  
                              • Slide 1
                              40034-V07H-50
                              40034-V07H-100
                              40034-V07H-10
                              50 µg 
                              100 µg 
                              10 µg 
                              Add to Cart
                              製品の説明: Active  
                              発現宿主: Human Cells  
                                40034-VNAHC-60
                                40034-VNAHC-500
                                60 U 
                                500 U 
                                Add to Cart
                                発現宿主: Human Cells  
                                • Slide 1
                                40040-V07H-50
                                40040-V07H-100
                                50 µg 
                                100 µg 
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                                反応度: C.perfringens  
                                アプリケーション: ELISA  WB  FCM  
                                  11680-RP02-50
                                  11680-RP02-200
                                  11680-RP02-100
                                  50 µg 
                                  200 µg 
                                  100 µg 
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                                  反応度: C.perfringens  
                                  アプリケーション: ELISA  WB  
                                    11680-RP01-400
                                    11680-RP01-200
                                    11680-RP01-100
                                    400 µg 
                                    200 µg 
                                    100 µg 
                                    Add to Cart
                                    反応度: C.perfringens  
                                    アプリケーション: ELISA  IF  ICC/IF  
                                      11680-R112-50
                                      11680-R112-100
                                      50 µg 
                                      100 µg 
                                      Add to Cart
                                      反応度: C.perfringens  
                                      アプリケーション: ELISA  WB  IP  
                                        11680-MM04-50
                                        11680-MM04-200
                                        11680-MM04-100
                                        50 µg 
                                        200 µg 
                                        100 µg 
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                                        反応度: H4N6  
                                        アプリケーション: ELISA  IHC-P  FCM  IF  IP  ICC/IF  
                                          40235-RP01-200
                                          40235-RP01-100
                                          200 µg 
                                          100 µg 
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                                          反応度: H4N6  
                                          アプリケーション: ELISA  WB  IHC-P  IP  
                                          • Slide 1
                                          40235-T60-50
                                          40235-T60-100
                                          50 µg 
                                          100 µg 
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                                          反応度: H7N7  
                                          アプリケーション: ELISA  WB  IHC-P  IP  
                                          • Slide 1
                                          40202-T60-50
                                          40202-T60-100
                                          50 µg 
                                          100 µg 
                                          Add to Cart
                                          反応度: H7N7  
                                          アプリケーション: ELISA  IHC-P  FCM  IF  IP  ICC/IF  
                                            40202-RP01-200
                                            40202-RP01-100
                                            200 µg 
                                            100 µg 
                                            Add to Cart
                                            反応度: Influenza  
                                            アプリケーション: ELISA  WB  FCM  IP  
                                              11058-R001-50
                                              11058-R001-100
                                              50 µg 
                                              100 µg 
                                              Add to Cart
                                              反応度: Influenza  
                                              アプリケーション: ELISA  WB  IP  
                                                11058-MM07-50
                                                11058-MM07-100
                                                50 µg 
                                                100 µg 
                                                Add to Cart

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                                                Neuraminidase cdna-clone 背景

                                                Neuraminidases are enzymes that cleave sialic acid groups from glycoproteins. Influenza neuraminidase is a type of neuraminidase found on the surface of influenza viruses that enables the virus to be released from the host cell.

                                                Influenza neuraminidase is composed of four identical subunits arranged in a square. It is normally attached to the virus surface through a long protein stalk. The active sites are in a deep depression on the upper surface. They bind to polysaccharide chains and clip off the sugars at the end. The surface of neuraminidase is decorated with several polysaccharide chains that are similar to the polysaccharide chains that decorate our own cell surface proteins.

                                                Neuraminidase (NA) and hemagglutinin (HA) are major membrane glycoproteins found on the surface of influenza virus. Hemagglutinin binds to the sialic acid-containing receptors on the surface of host cells during initial infection and at the end of an infectious cycle. Neuraminidase, on the other hand, cleaves the HA-sialic acid bondage from the newly formed virions and the host cell receptors during budding. Neuraminidase thus is described as a receptor-destroying enzyme which facilitates virus release and efficient spread of the progeny virus from cell to cell.

                                                Influenza antibody and influenza antibodies are very important research tools for influenza diagnosis, influenza vaccine development, and anti-influenza virus therapy development. Monoclonal or polyclonal antibody can be raised with protein based antigen or peptide based antigen. Antibody raised with protein based antigen could have better specificity and/or binding affinity than antibody raised with peptide based antigen, but cost associated with the recombinant protein antigen is usually higher. Anti influenza virus hemagglutinin (HA) monoclonal antibody or polyclonal antibody can be used for ELISA assay, western blotting detection, Immunohistochemistry (IHC), flow cytometry, neutralization assay, hemagglutinin inhibition assay, and early diagnosis of influenza viral infection.

                                                Sino Biological has developed state-of-the-art monoclonal antibody development technology platforms: mouse monoclonal antibody and rabbit monoclonal antibody. Our rabbit monoclonal antibody platform is one of a kind and offers some unique advantages over mouse monoclonal antibodies, such as high affinity, low cross-reactivity with rabbit polyclonal antibodies.

                                                H5N8 Neuraminidase cdna-clone 参考文献
                                              • Sardet C., et al.,(1989), Molecular cloning, primary structure, and expression of the human growth factor-activatable Na+/H+ antiporter. Cell 56:271-280.
                                              • Sardet C., et al., (1990), Growth factors induce phosphorylation of the Na+/H+ antiporter, glycoprotein of 110 kD.Science 247:723-726.
                                              • Tse C.-M., et al.,(1991), Molecular cloning and expression of a cDNA encoding the rabbit ileal villus cell basolateral membrane Na+/H+ exchanger.EMBO J. 10:1957-1967.
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