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PPC-DC / PPCDC 抗体, ウサギポリクローナル抗体


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PPC-DC / PPCDC antibody 背景

PPC-DC, also known as PPCDC, belongs to the HFCD (homo oligomeric flavin containing Cys decarboxylase) superfamily which takes a part in the biosynthesis of coenzyme A (CoA) from pantothenate (Vitamin B). Biosynthesis of coenzyme A (CoA) from pantothenic acid (vitamin B5) is an essential universal pathway in prokaryotes and eukaryotes. This process include several steps: the phosphorylation of pantothenate, the conversion of 4’-hosphopantothenate to 4''-phosphopantetheine, the adenylation by phosphopantetheine adenylyltransferase to form dephospho-CoA and the phosphorylation by dephospho-CoA kinase to form CoA. PPC-DC, one of the last enzymes in this pathway, converts phosphopantothenoylcysteine to 4-prime-phosphopantetheine.

人々 PPC-DC / PPCDC antibody 参考文献
  • Zody MC. et al., 2006, Nature. 440: 671-5.
  • Ota T. et al., 2004, Nat Genet. 36: 40-5.
  • Clark HF. et al., 2003, Genome Res. 13: 2265-70.
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