Text Size:AAA

FSTL1 抗体, ウサギポリクローナル抗体

データシートレビュープロトコル
発現宿主: Human Cells  
  • Slide 1
80885-H08H-50
80885-H08H-200
50 µg 
200 µg 
Add to Cart
発現宿主: Human Cells  
  • Slide 1
10924-H08H-50
10924-H08H-100
50 µg 
100 µg 
Add to Cart
発現宿主: Human Cells  
  • Slide 1
51127-M08H-50
51127-M08H-100
50 µg 
100 µg 
Add to Cart
発現宿主: Human Cells  
  • Slide 1
51127-M02H-50
51127-M02H-100
50 µg 
100 µg 
Add to Cart

FSTL1 AntibodyRelated Products

Related Products

Featured Reagent Products

FSTL1 antibody 背景

Follistatin-related protein 1 (FSTL1)  is an extracellular glycoprotein whose functional significance in physiological and pathological processes is incompletely understood. Recently, we have shown that FSTL1 acts as a muscle-derived secreted factor that is up-regulated by Akt activation and ischemic stress and that FSTL1 exerts favorable actions on the heart and vasculature. Here, we sought to identify the receptor that mediates the cellular actions of FSTL1. It contains an FS module, a follistatin-like sequence containing 10 conserved cysteine residues. FSTL1 is thought to be an autoantigen associated with rheumatoid arthritis. DIP2A functions as a novel receptor that mediates the cardiovascular protective effects of FSTL1. Experiment results have provided in vivo and in vitro evidence to demonstrate that Fstl1 modulates lung development and alveolar maturation, in part, through BMP4 signaling.

マウス FSTL1 antibody 参考文献
  • Rosenberg MI, et al. (2006) MyoD inhibits Fstl1 and Utrn expression by inducing transcription of miR-206. J Cell Biol. 175(1): 77-85.
  • Ouchi N, et al. (2010) DIP2A functions as a FSTL1 receptor. J Biol Chem. 285(10): 7127-34.
  • Geng Y, et al. (2011) Follistatin-like 1 (Fstl1) is a bone morphogenetic protein (BMP) 4 signaling antagonist in controlling mouse lung development. Proc Natl Acad Sci U S A. 108(17): 7058-63.
  • 注意:すべての製品は、"研究目的のみに使用するものであり、診断または治療目的に使用するものではありません"