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マウス S100A9/MRP-14 Gene ORF cDNA clone expression plasmid, C-His タグ

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製品の説明: Active  
発現宿主: E. coli  
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11145-HNAE-50
11145-HNAE-100
50 µg 
100 µg 
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製品の説明: Active  
発現宿主: Baculovirus-Insect Cells  
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11145-H08B-50
11145-H08B-100
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100 µg 
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発現宿主: E. coli  
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50284-M07E-50
50284-M07E-100
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100 µg 
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反応度: Human  
アプリケーション: ELISA  
    11145-RP01-400
    11145-RP01-200
    11145-RP01-100
    400 µg 
    200 µg 
    100 µg 
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    反応度: Human  
    アプリケーション: FCM  
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    11145-MM01-F-25
    11145-MM01-F-100
    25 Test 
    100 Tests 
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    反応度: Human  
    アプリケーション: ELISA  IHC-P  
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    • Slide 1
    11145-RP02-50
    11145-RP02-200
    11145-RP02-100
    50 µg 
    200 µg 
    100 µg 
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    反応度: Human  
    アプリケーション: IHC-P  
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    11145-R209-50
    11145-R209-100
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    100 µg 
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    反応度: Human  
    アプリケーション: ELISA  WB  
      11145-R018-50
      11145-R018-100
      50 µg 
      100 µg 
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      反応度: Human  
      アプリケーション: FCM  IF  ICC/IF  
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      • Slide 1
      11145-MM01-50
      11145-MM01-200
      11145-MM01-100
      50 µg 
      200 µg 
      100 µg 
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      反応度: Human  
      アプリケーション: FCM  
      • Slide 1
      11145-MM01-P-25
      11145-MM01-P-100
      25 Test 
      100 Tests 
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      反応度: Mouse  
      アプリケーション: 
      • Slide 1
      50284-T24-50
      50284-T24-200
      50284-T24-100
      50 µg 
      200 µg 
      100 µg 
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      S100A9/MRP-14 cdna-clone 背景

      S100 protein is a family of low molecular weight protein found in vertebrates characterized by two EF-hand calcium-binding motifs. There are at least 21 different S100 proteins, and the name is derived from the fact that the protein is 100% soluble in ammonium sulfate at neutral pH. Most S100 proteins are disulfide-linked homodimer, and is normally present in cells derived from the neural crest, chondrocytes, macrophages, dendritic cells, etc. S100 proteins have been implicated in a variety of intracellular and extracellular functions. They are involved in regulation of protein phosphorylation, transcription factors, the dynamics of cytoskeleton constituents, enzyme activities, cell growth and differentiation, and the inflammatory response. Protein S100-A9, also known as S100 calcium-binding protein A9, S100A9, and CAGB, is a member of the S-100 family. S100A9 is expressed by macrophages in acutely inflammed tissues and in chronic inflammation. It is also expressed in epithelial cells constitutively or induced during dermatoses. S100A9 is a calcium-binding protein. It has anti-microbial activity towards bacteria and fungi. The anti-microbial and proapoptotic activity of S100A9 is inhibited by zinc ions. S100A9 plays a role in the development of endotoxic shock in response to bacterial lipopolysaccharide (LPS). It promotes tubulin polymerization when unphosphorylated. It also promotes phagocyte migration and infiltration of granulocytes at sites of wounding. S100A9 plays a role as a pro-inflammatory mediator in acute and chronic inflammation and up-regulates the release of IL8 and cell-surface expression of ICAM1.

      マウス S100A9/MRP-14 cdna-clone 参考文献
    • Miyasaki KT. et al., 1993, J Dent Res. 72: 517-23.
    • Fanò G. et al., 1995, Prog Neurobiol. 46 (1): 71-82.
    • Vogl T. et al., 2004, Blood. 104: 4260-8.
    • Viemann D. et al., 2005, Blood. 105: 2955-62.
    • Nakatani Y. et al., 2005, Mediators Inflamm. 2005: 280-92.
    • Bjoerk P. et al., 2009, PLoS Biol. 7: E97-E97.
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