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人々 Moesin Gene ORF cDNA clone expression plasmid, N-HA タグ

データシートレビュープロトコル
発現宿主: E. coli  
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13659-H07E-20
13659-H07E-100
20 µg 
100 µg 
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反応度: Human  
アプリケーション: ELISA  
    13659-RP01-400
    13659-RP01-200
    13659-RP01-100
    400 µg 
    200 µg 
    100 µg 
    Add to Cart
    反応度: Human  
    アプリケーション: ELISA  
      13659-T16-50
      13659-T16-200
      13659-T16-100
      50 µg 
      200 µg 
      100 µg 
      Add to Cart

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      Moesin cdna-clone 背景

      Moesin is a member of the ERM family which includes ezrin and radixin. ERM proteins, highly related members of the larger protein 4.1 superfamily, can exist in an active or inactive conformation. It seems that ERM proteins function as cross-linkers between plasma membranes and actin-based cytoskeletons. The sole Drosophila ERM protein, moesin, functions to promote cortical actin assembly and apical-basal polarity. As a result, cells lacking moesin lose epithelial characteristics and adopt invasive migratory behaviour. It is localized to filopodia and other membranous protrusions that are important for cell-cell recognition and signaling and for cell movement. Moesin contains 1 FERM domain and is expressed in all tissues and cultured cells studied. Moesin has been shown to interact with CD43, Neutrophil cytosolic factor 1, VCAM-1, Neutrophil cytosolic factor 4, ICAM3 and EZR.

      人々 Moesin cdna-clone 参考文献
    • Lankes WT, et al. (1991) Moesin: a member of the protein 4.1-talin-ezrin family of proteins. Proc Natl Acad Sci. 88(19):8297-301.
    • Serrador, J M, et al. (1998) CD43 interacts with moesin and ezrin and regulates its redistribution to the uropods of T lymphocytes at the cell-cell contacts. Blood. 91(12):4632-44.
    • Barreiro Olga, et al. (2002) Dynamic interaction of VCAM-1 and ICAM-1 with moesin and ezrin in a novel endothelial docking structure for adherent leukocytes. J Cell Biol. 157(7):1233-45.
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