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マウス AK4 / Adenylate Kinase 4 / AK3L1 Gene ORF cDNA clone expression plasmid, N-Flag タグ

データシートレビュープロトコル
反応度: Human  
アプリケーション: ELISA  
    12406-MM04-50
    12406-MM04-200
    12406-MM04-100
    50 µg 
    200 µg 
    100 µg 
    Add to Cart
    反応度: Human  
    アプリケーション: FCM  
    • Slide 1
    12406-MM09-P-25
    12406-MM09-P-100
    25 Test 
    100 Tests 
    Add to Cart
    反応度: Human  
    アプリケーション: WB  IF  IP  ICC/IF  
    • Slide 1
    • Slide 1
    • Slide 1
    12406-R010-50
    12406-R010-100
    50 µg 
    100 µg 
    Add to Cart
    反応度: Human  
    アプリケーション: ELISA  IP  
    • Slide 1
    12406-R014-50
    12406-R014-100
    50 µg 
    100 µg 
    Add to Cart
    反応度: Human  
    アプリケーション: ELISA  
      12406-RP01-400
      12406-RP01-200
      12406-RP01-100
      400 µg 
      200 µg 
      100 µg 
      Add to Cart
      反応度: Human  
      アプリケーション: FCM  IF  ICC/IF  
      • Slide 1
      • Slide 1
      12406-MM09-50
      12406-MM09-200
      12406-MM09-100
      50 µg 
      200 µg 
      100 µg 
      Add to Cart
      反応度: Human  
      アプリケーション: ELISA  WB  IP  
      • Slide 1
      • Slide 1
      12406-MM08-50
      12406-MM08-200
      12406-MM08-100
      50 µg 
      200 µg 
      100 µg 
      Add to Cart
      反応度: Human  
      アプリケーション: ELISA  WB  IP  
      • Slide 1
      • Slide 1
      12406-RP02-50
      12406-RP02-200
      12406-RP02-100
      50 µg 
      200 µg 
      100 µg 
      Add to Cart

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      AK4 / Adenylate Kinase 4 / AK3L1 cdna-clone 背景

      Adenylate kinase isoenzyme 4, mitochondrial, also known as ATP-AMP transphosphorylase, Adenylate kinase 3-like, AK4 and AK3L1, is a member the adenylate kinase family. AK4 / AK3L1 is localized to the mitochondrial matrix. Adenylate kinases regulate the adenine and guanine nucleotide compositions within a cell by catalyzing the reversible transfer of phosphate group among these nucleotides. Five isozymes of adenylate kinase have been identified in vertebrates. Expression of these isozymes is tissue-specific and developmentally regulated. AK4 / AK3L1 catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. It may also be active with GTP. Adenylate kinase 4 ( AK4 / AK3L1 ) is a unique member with no enzymatic activity in the adenylate kinase (AK) family although it shares high sequence homology with other AKs. It remains unclear what physiological function AK4 might play or why it is enzymatically inactive. AK4 / AK3L1 retains the capability of binding nucleotides. It has a glutamine residue instead of a key arginine residue in the active site well conserved in other AKs. The enzymatically inactive AK4 is a stress responsive protein critical to cell survival and proliferation. AK4 / AK3L1 is likely that the interaction with the mitochondrial inner membrane protein ANT is important for AK4 to exert the protective benefits to cells under stress. AK4 / AK3L1 also acts on the specific mechanism of energy metabolism rather than control of the homeostasis of the ADP pool ubiquitously.

      マウス AK4 / Adenylate Kinase 4 / AK3L1 cdna-clone 参考文献
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