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VEGFR1 / FLT-1 抗体, ウサギポリクローナル抗体, Antigen Affinity Purified

データシートレビュープロトコル
製品の説明: Active  
発現宿主: Human Cells  
  • Slide 1
10136-H08H-50
10136-H08H-100
50 µg 
100 µg 
Add to Cart
製品の説明:   
発現宿主: Human Cells  
  • Slide 1
10136-H08H1-50
10136-H08H1-100
50 µg 
100 µg 
Add to Cart
発現宿主: Human Cells  
  • Slide 1
10136-H02H-50
10136-H02H-20
50 µg 
20 µg 
Add to Cart
製品の説明: Active  
発現宿主: Human Cells  
  • Slide 1
80101-R08H-50
80101-R08H-100
50 µg 
100 µg 
Add to Cart

HP100207 

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VEGFR1/FLT-1 antibody 背景

Vascular endothelial growth factor receptor 1, also known as VEGFR-1, Fms-like tyrosine kinase 1, Tyrosine-protein kinase FRT, Tyrosine-protein kinase receptor FLT, Vascular permeability factor receptor and FLT1, is a single-pass type I membrane protein and secreted protein which belongs to the protein kinase superfamily, Tyr protein kinase family and CSF-1/PDGF receptor subfamily. VEGFR-1 / FLT1 contains seven Ig-like C2-type (immunoglobulin-like) domains and one protein kinase domain. VEGFR-1 / FLT1 is expressed mostly in normal lung, but also in placenta, liver, kidney, heart and brain tissues. It is specifically expressed in most of the vascular endothelial cells, and also expressed in peripheral blood monocytes. VEGFR-1 / FLT1 is not expressed in tumor cell lines. VEGFR-1 / FLT1 is an essential receptor tyrosine kinase that regulates mammalian vascular development and embryogenesis. EGF-induced angiogenesis requires inverse regulation of VEGFR-1 and VEGFR-2 in tumor-associated endothelial cells. VEGFR-1 / FLT1 is a receptor for VEGF, VEGFB and PGF. It has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability.

Immune Checkpoint   Immunotherapy   Cancer Immunotherapy   Targeted Therapy

人々 VEGFR1/FLT-1 antibody 参考文献
注意:すべての製品は、"研究目的のみに使用するものであり、診断または治療目的に使用するものではありません"