クイック注文

人々 IL1R1 / CD121a 蛋白質

データシートレビュープロトコル
反応度: Human  
アプリケーション: ELISA  
    10126-MM10-50
    10126-MM10-200
    10126-MM10-100
    50 µg 
    200 µg 
    100 µg 
    Add to Cart
    反応度: Human  
    アプリケーション: 
      10126-MM08-50
      10126-MM08-200
      10126-MM08-100
      10126-MM08-1
      50 µg 
      200 µg 
      100 µg 
      1 mg 
      Add to Cart
      反応度: Human  
      アプリケーション: ELISA  
        10126-RP01-400
        10126-RP01-200
        10126-RP01-100
        400 µg 
        200 µg 
        100 µg 
        Add to Cart
        反応度: Human  
        アプリケーション: ELISA  WB  IP  
        • Slide 1
        • Slide 1
        10126-RP02-50
        10126-RP02-200
        10126-RP02-100
        50 µg 
        200 µg 
        100 µg 
        Add to Cart
        反応度: Human  
        アプリケーション: ELISA  
          10126-R024-50
          10126-R024-100
          50 µg 
          100 µg 
          Add to Cart
          反応度: Mouse  
          アプリケーション: FCM  
          • Slide 1
          50807-R191-A-25
          50807-R191-A-100
          25 Test 
          100 Tests 
          Add to Cart
          反応度: Mouse  
          アプリケーション: ELISA  
            50807-RP01-400
            50807-RP01-200
            50807-RP01-100
            400 µg 
            200 µg 
            100 µg 
            Add to Cart
            反応度: Mouse  
            アプリケーション: ELISA  
              50807-T16-50
              50807-T16-200
              50807-T16-100
              50 µg 
              200 µg 
              100 µg 
              Add to Cart
              反応度: Mouse  
              アプリケーション: FCM  
              • Slide 1
              50807-R191-P-25
              50807-R191-P-100
              25 Test 
              100 Tests 
              Add to Cart
              反応度: Mouse  
              アプリケーション: ELISA  
                50807-R002-50
                50807-R002-100
                50807-R002-1
                50 µg 
                100 µg 
                1 mg 
                Add to Cart
                反応度: Mouse  
                アプリケーション: FCM  
                • Slide 1
                50807-R191-50
                50807-R191-100
                50 µg 
                100 µg 
                Add to Cart
                反応度: Mouse  
                アプリケーション: ELISA  
                  50807-R075-50
                  50807-R075-100
                  50 µg 
                  100 µg 
                  Add to Cart
                  反応度: Rat  
                  アプリケーション: FCM  
                  • Slide 1
                  80028-R007-F-25
                  80028-R007-F-100
                  25 Test 
                  100 Tests 
                  Add to Cart
                  反応度: Rat  
                  アプリケーション: 
                    80028-MM10-50
                    80028-MM10-200
                    80028-MM10-100
                    80028-MM10-1
                    50 µg 
                    200 µg 
                    100 µg 
                    1 mg 
                    Add to Cart
                    反応度: Rat  
                    アプリケーション: ELISA  
                      80028-MM08-50
                      80028-MM08-200
                      80028-MM08-100
                      80028-MM08-1
                      50 µg 
                      200 µg 
                      100 µg 
                      1 mg 
                      Add to Cart
                      反応度: Rat  
                      アプリケーション: ELISA  
                      • Slide 1
                      80028-R007-50
                      80028-R007-100
                      50 µg 
                      100 µg 
                      Add to Cart
                      反応度: Rat  
                      アプリケーション: ELISA  WB  
                      • Slide 1
                      80028-RP02-50
                      80028-RP02-200
                      80028-RP02-100
                      50 µg 
                      200 µg 
                      100 µg 
                      Add to Cart
                      反応度: Rat  
                      アプリケーション: ELISA  
                        80028-R027-50
                        80028-R027-100
                        50 µg 
                        100 µg 
                        Add to Cart
                        反応度: Rat  
                        アプリケーション: ELISA  
                          80028-RP01-400
                          80028-RP01-200
                          80028-RP01-100
                          400 µg 
                          200 µg 
                          100 µg 
                          Add to Cart
                          反応度: Rat  
                          アプリケーション: FCM  
                          • Slide 1
                          80028-R007-P-25
                          80028-R007-P-100
                          25 Test 
                          100 Tests 
                          Add to Cart
                          反応度: Cynomolgus  
                          アプリケーション: ELISA  
                            90279-T16-50
                            90279-T16-200
                            90279-T16-100
                            50 µg 
                            200 µg 
                            100 µg 
                            Add to Cart
                            反応度: Cynomolgus  
                            アプリケーション: ELISA  
                              90279-MM02-50
                              90279-MM02-200
                              90279-MM02-100
                              50 µg 
                              200 µg 
                              100 µg 
                              Add to Cart

                              IL1R1/IL-1R1/IL-1 RI ELISA Pair Set

                              検出限界:
                              SEK50807-5
                              SEK50807-15
                              5 Plates 
                              15 Plates 
                              Add to Cart
                              検出限界: 62.5 pg/ml
                              SEK80028-5
                              SEK80028-15
                              5 Plates 
                              15 Plates 
                              Add to Cart

                              IL1R1/IL-1R1/IL-1 RI Recombinant ProteinRelated Products

                              Related Products

                              Featured Reagent Products

                              IL1R1/IL-1R1/IL-1 RI protein 背景

                              Interleukin 1 receptor, type I (IL-1R1) also known as CD121a (Cluster of Differentiation 121a), is an interleukin receptor. IL-1R1/CD121a is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein is a receptor for interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I (IL1R1/IL1RA). IL-1R1/CD121a is an important mediator involved in many cytokine induced immune and inflammatory responses. This protein has been characterized by pharmacological and molecular techniques in the mouse brain. The spindle-shaped astrocytes enclose the wound, separating the healthy from damaged neural tissue. The shape change and subsequent repair processes are IL-1β activity-dependent, acting through the IL-1 type 1 receptor (IL-1R1), as co-application of the IL-1type 1 receptor antagonist protein (IL-1ra) blocks IL-1β induced effects. In the spleen, a slight increase in IL-1R AcP and IL-1R1 was observed during the first hours following LPS stimulation. In conclusion, IL-1R AcP mRNA is expressed in the brain and in other tissues where IL-1R1/CD121a transcripts are found. However, the regulation of its expression is distinct from IL-1R1/CD121a. The high level of expression and the lack of regulation of IL-1R AcP transcripts in the brain under inflammatory conditions suggest that the protein might be constitutively expressed in excess.

                              人々 IL1R1/IL-1R1/IL-1 RI protein 参考文献
                            • Dale M, et al. (1999). "Interleukin-1 receptor cluster: gene organization of IL1R2, IL1R1, IL1RL2 (IL-1Rrp2), IL1RL1 (T1/ST2), and IL18R1 (IL-1Rrp) on human chromosome 2q.". Genomics 57 (1): 177-9.
                            • Joos L, et al. (2001). "Association of IL-1beta and IL-1 receptor antagonist haplotypes with rate of decline in lung function in smokers.". Thorax 56 (11): 863-6.
                            • Vigers GP, et al. (1997). "Crystal structure of the type-I interleukin-1 receptor complexed with interleukin-1beta.". Nature 386 (6621): 190-4.
                            • 注意:すべての製品は、"研究目的のみに使用するものであり、診断または治療目的に使用するものではありません"