ACE cDNA ORF Clone, Rat, C-DYKDDDDK (Flag®) tag

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ACE cDNA ORF Clone, Rat, C-DYKDDDDK (Flag®) tag: 製品情報

遺伝子
Rat
NCBI 参考シーケンス番号
遺伝子の長さ
3942 bp
製品の特徴
Full length Clone DNA of Rat angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 with C terminal Flag tag.
プラスミド
プロモーター
Enhanced CMV promoter
ベクター
タグシーケンス
FLAG Tag Sequence: GATTACAAGGATGACGACGATAAG
シークエンシングプライマー
T7( 5' TAATACGACTCACTATAGGG 3' )
BGH( 5' TAGAAGGCACAGTCGAGG 3' )
品質管理
The plasmid is confirmed by full-length sequencing.
スクリーニング
細菌スクリーニング抵抗力
Kanamycin
細胞スクリーニング抵抗力
Hygromycin
アプリケーション
Stable or Transient mammalian expression
保存 & 配送
配送方法
Each tube contains lyophilized plasmid.
保存条件
The lyophilized plasmid can be stored at ambient temperature for three months.
Note: Flag® is a registered trademark of Sigma Aldrich Biotechnology LP. It is used here for informational purposes only.

ACE 背景情報

Angiotensin I-converting enzyme (ACE) is a zinc dipeptidyl carboxypeptidase that plays a critical role in the regulation of the renin-angiotensin system. Hypertension is an important factor in cardiovascular diseases. Angiotensin-I-converting enzyme (ACE) inhibitors like synthetic drugs are widely used to control hypertension. It has been shown that ACE can also act as a transducer signal molecule when its inhibitors or substrates bind to it. This new role of ACE could contribute to understanding some of the effects not explained by its catalytic activity only.
完全な名称
angiotensin I converting enzyme
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