Caspase-7 (Protein|Antibody|cDNA Clone|ELISA Kit)

All Caspase-7 reagents are produced in house and quality controlled, including 17 Caspase-7 Gene, 1 Caspase-7 Protein, 1 Caspase-7 qPCR. All Caspase-7 reagents are ready to use.

Recombinant Caspase-7 proteins are expressed by E. coli with fusion tags as C-His.

Caspase-7 cDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each Caspase-7 of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.

Caspase-7 Protein (1)

Species

Caspase-7 Protein, Human, Recombinant (His Tag)

10049-H08E

Expression host: E. coli

Human Caspase-7/MCH3 Protein 8336
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Caspase-7 cDNA Clone (17)

Rat
Human

Caspase-7 qPCR Primer (1)

Caspase 7, also known as caspase-7 and MCH3, belongs to the cysteine-aspartic acid protease (caspase) family. Caspases play a role in the signal transduction pathways of apoptosis, necrosis and inflammation. There are two major classes of caspases: initiators and effectors. The initiator isoforms (caspases-1,-4,-5,-8,-9,-1,-11,-12) are activated by, and interact with, upstream adaptor molecules through protein-protein interaction domains known as CARD and DED. Effector caspases (-3,-6,-7) are responsible for cleaving downstream substrates and are sometimes referred to as the executioner caspases. Caspase 7 exists in lung, skeletal muscle, liver, kidney, spleen and heart, and moderately in testis. Caspase 7 cannot be detected in the brain. Caspase 7 functions in the activation cascade of caspases responsible for apoptosis execution. It cleaves and activates sterol regulatory element binding proteins (SREBPs). It proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp- -Gly-217' bond. Overexpression promotes programmed cell death.
Protein
Gene
qPCR
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