Anti-CD48 Antibody

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Anti-CD48 Antibody (Rabbit Monoclonal 抗体) の製品情報

製品名
Anti-CD48 Antibody
検証済のアプリケーション
FCM
交差反応
Reacts with: Rat
特異性
Rat CD48
免疫原
Recombinant Rat CD48 / SLAMF2 Protein (Catalog#80286-R08H)
調製
This antibody was obtained from a rabbit immunized with purified, recombinant Rat CD48 / SLAMF2 (rR CD48 / SLAMF2; Catalog#80286-R08H; P10252; Met1-Arg216).
ソース
Monoclonal Rabbit IgG Clone #002
精製
Protein A
緩衝液
0.2 μm filtered solution in PBS
標識物
Unconjugated
状態
Liquid
配送方法
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
保存条件
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Anti-CD48 Antibody (Rabbit Monoclonal 抗体) 検証済のアプリケーション

アプリケーション 推奨希釈率/用量
FCM 1:25-1:100
Please Note: Optimal concentrations/dilutions should be determined by the end user.

Anti-CD48 Antibody (Rabbit Monoclonal 抗体) の画像

Flow cytometric analysis of Rat CD48 expression on SD rat splenocytes. Cells were stained with purified anti-Rat CD48, then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells.

CD48 背景情報

Cluster of Differentiation 48 (CD48), also known as SLAMF2, BCM-1 and BLAST-1, is a GPI-linked protein belonging to the CD2 subfamily of immunoglobulin superfamily molecules. CD2 and 2B4 (CD244) are known ligands for CD48. CD48 protein is expressed on most lineage-committed hematopoietic cells but not on hematopoietic stem cells or multipotent hematopoietic progenitors. CD48 protein performs biological functions in a variety processes including adhesion, pathogen recognition, cellular activation, and cytokine regulation, and emerges as a critical effector molecule in immune responses.
完全な名称
CD48 molecule
参考文献
  • Messmer B, et al. (2006) CD48 stimulation by 2B4 (CD244)-expressing targets activates human NK cells. J Immunol. 176(8): 4646-50
  • Milstein O, et al. (2008) Nanoscale increases in CD2-CD48-mediated intermembrane spacing decrease adhesion and reorganize the immunological synapse. J Biol Chem. 283(49): 34414-22.

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