Anti-FGF1 Antibody

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Anti-FGF1 Antibody (Rabbit Polyclonal 抗体) の製品情報

製品名
Anti-FGF1 Antibody
検証済のアプリケーション
ICC/IF
交差反応
Reacts with: Human
特異性
Human FGF1
免疫原
E. coli-derived Human FGF1 fragment
調製
Produced in rabbits immunized with E. coli-derived Human FGF1 fragment, and purified by antigen affinity chromatography.
ソース
Polyclonal Rabbit IgG
精製
Protein A & Antigen Affinity
緩衝液
PBS, pH7.0 with 0.03% Proclin300
標識物
Unconjugated
状態
Liquid
配送方法
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
保存条件
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Avoid repeated freeze-thaw cycles.

Anti-FGF1 Antibody (Rabbit Polyclonal 抗体) 検証済のアプリケーション

アプリケーション 推奨希釈率/用量
ICC-IF 1:100-1:500
Please Note: Optimal concentrations/dilutions should be determined by the end user.

Anti-FGF1 Antibody (Rabbit Polyclonal 抗体) の画像

Immunofluorescence staining of FGF1 in HepG2 cells. Cells were fixed with 4% PFA, permeabilzed with 0.1% Triton X-100 in PBS,blocked with 10% serum, and incubated with rabbit anti-Human FGF1 polyclonal antibody (dilution ratio 1:200) at 4℃ overnight. Then cells were stained with the Alexa Fluor®488-conjugated Goat Anti-rabbit IgG secondary antibody (green) and counterstained with DAPI (blue).Positive staining was localized to Cytoplasm.

Anti-FGF1 Antibody: 別名

Anti-AFGF Antibody; Anti-ECGF Antibody; Anti-ECGF-beta Antibody; Anti-ECGFA Antibody; Anti-ECGFB Antibody; Anti-FGF-1 Antibody; Anti-FGF-alpha Antibody; Anti-FGFA Antibody; Anti-GLIO703 Antibody; Anti-HBGF-1 Antibody; Anti-HBGF1 Antibody

FGF1 背景情報

aFGF, also known as FGF1 and HBGF-1, is a member of the fibroblast growth factor family. The biological activity of aFGF protein is exerted through binding to four high affinity cell surface receptors (FGFR1–4), which results in receptor dimerization and transphosphorylation in the tyrosine kinase domain. aFGF protein shows a wide range of endocrine-like activities. As a multiple function growth factor, this protein is involved in embryo development and tissue repair. Additionally, this protein is considered to function in several important physiological and pathological processes, such as embryonic development, morphogenesis, angiogenesis, wound healing and atheromatosis, carcinogenesis, development, and invasion of cancer.

References

完全な名称
fibroblast growth factor 1 (acidic)
参考文献
  • Jaye M., et al.,(1986), Human endothelial cell growth factor: cloning, nucleotide sequence, and chromosome localization. Science 233:541-545.
  • Mergia A., et al., (1989), Structural analysis of the gene for human acidic fibroblast growth factor.Biochem. Biophys. Res. Commun. 164:1121-1129.
  • Wang W.P., et al.,(1989), Cloning of the gene coding for human class 1 heparin-binding growth factor and its expression in fetal tissues.Mol. Cell. Biol. 9:2387-2395.

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