Lymphotactin / XCL1 (タンパク質 | 抗体 | cDNA クローン | ELISA キット)

All Lymphotactin / XCL1 reagents are produced in house and quality controlled, including 8 Lymphotactin / XCL1 Antibody, 1 Lymphotactin / XCL1 ELISA, 52 Lymphotactin / XCL1 Gene, 4 Lymphotactin / XCL1 Lysate, 4 Lymphotactin / XCL1 Protein, 2 Lymphotactin / XCL1 qPCR. All Lymphotactin / XCL1 reagents are ready to use.

Lymphotactin / XCL1 関連の研究分野

Lymphotactin / XCL1 の背景知識

This antimicrobial gene encodes a member of the chemokine superfamily. Chemokines function in inflammatory and immunological responses, inducing leukocyte migration and activation. The encoded protein is a member of the C-chemokine subfamily, retaining only two of four cysteines conserved in other chemokines, and is thought to be specifically chemotactic for T cells. This gene and a closely related family member are located on the long arm of chromosome 1.

Lymphotactin / XCL1 の参考文献

  • Nguyen KD, et al. (2008) XCL1 enhances regulatory activities of CD4+ CD25(high) CD127(low/-) T cells in human allergic asthma. J Immunol. 181 (8): 5386-95.
  • Dong C, et al. (2005) Glycosylated recombinant human XCL1 / lymphotactin exhibits enhanced biologic activity. J Immunol Methods. 302 (1-2): 136-44.
  • Zavala-Flores LM, et al. (2009) Production of biologically active human lymphotactin (XCL1) by Lactococcus lactis. Biotechnol Lett. 31 (2): 215-20.
  • Guzzo C, Fox JC, Miao H, Volkman BF, Lusso P. Structural Determinants for the Selective Anti-HIV-1 Activity of the All-β Alternative Conformer of XCL1. Kirchhoff F, ed. Journal of Virology. 2015;89(17):9061-9067.