After search, choose a molecule or a kind of categories listed in the left to narrow down your filter. If you have any problems, please contact us!

クイック注文

Text Size:AAA

UCHL3 抗体, ウサギモノクローナル抗体

データシートレビュー関連製品プロトコル
Rat UCHL3 抗体製品情報
免疫原:Recombinant Rat UCHL3 protein (Catalog#80087-R07E)
Clone ID:007
Ig タイプ:Rabbit IgG
濃度:
エンドトキシン:
製剤:0.2 μm filtered solution in PBS with 5% trehalose
調製:This antibody was obtained from a rabbit immunized with purified, recombinant Rat UCHL3 (rR UCHL3; Catalog#80087-R07E; Q91Y78; Glu2-Ala230).
Rat UCHL3 抗体使用ガイド
特異度:Rat UCHL3
Has cross-reactivity in ELISA with
Human UCHL3
Mouse UCHL3
アプリケーション:WB, ELISA, IHC-P, IP

WB: 2-5 μg/mL

ELISA: 0.1-0.2 μg/mL

This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Rat UCHL3. The detection limit for Rat UCHL3 is approximately 0.0049 ng/well.

IHC-P: 1-10 μg/mL

IP: 1-4 μg/mg of lysate

保存:This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
Rat UCHL3 Antibody WB Application Image
Rat UCHL3 Antibody IHC Application Image
UCHL3 Antibody, Rabbit MAb, Immunohistochemistry
[クリックして画像を拡大]
Caption:
Immunochemical staining of rat UCHL3 in rat testis with rabbit monoclonal antibody (5 µg/mL, formalin-fixed paraffin embedded sections).
Rat UCHL3 Antibody IP Application Image
Other UCHL3 Antibody Products
UCHL3 背景

Ubiquitin carboxyl-terminal hydrolase isozyme L3, also known as UCH-L3, Ubiquitin thioesterase L3 and UCHL3, is a ubiquitin-protein hydrolase which belongs to the peptidase C12 family. It is involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. This enzyme is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of either ubiquitin or NEDD8. UCHL3 is highly expressed in heart, skeletal muscle, and testis. UCHL1 and UCHL3 are two of the deubiquitinating enzymes expressed in the brain. These phenotypes indicate the importance of UCHL1 and UCHL3 in the regulation of the central nervous system. UCHL3 functions as a de-ubiquitinating enzyme where lack of its hydrolase activity may result in the prominent accumulation of ubiquitinated proteins and subsequent induction of stress responses in skeletal muscle. UCHL3 has also been identified as a tumor-specific antigen in colon cancer.

Rat UCHL3 参考文献
  • Wood,M.A. et al., 2005, Hippocampus  15 (5):610-21.
  • Kwon,J. et al., 2006, Exp Anim  55 (1):35-43.
  • Setsuie,R. et al., 2009, Neurochem Int  54 (5-6):314-21.
  • Setsuie,R. et al., 2010, Neurochem Int  56 (8):911-8.
  • Product nameProduct name
    Size / Price
    カタログ: 80087-R007-50
    定価: 
    価格:      (You Save: )
    All information of our products is subject to change without notice. Please refer to COA enclosed in shipped package for the newest information.
    注意:すべての製品は、"研究目的のみに使用するものであり、診断または治療目的に使用するものではありません"