DR5 (Protein|Antibody|cDNA Clone|ELISA Kit)

All DR5 reagents are produced in house and quality controlled, including 9 DR5 Antibody, 27 DR5 Gene, 4 DR5 Lysate, 4 DR5 Protein, 2 DR5 qPCR. All DR5 reagents are ready to use.

Recombinant DR5 proteins are expressed by HEK293 Cells with fusion tags as C-human IgG1-Fc & His, C-His.

DR5 antibodies are validated with different applications, which are ELISA, FCM.

DR5 cDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each DR5 of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.

DR5 Protein (4)

Species

DR5 Protein, Human, Recombinant (His Tag)

10465-H08H

Expression host: HEK293 Cells

Human TRAIL R2/CD262/TNFRSF10B Protein 8837

DR5 Protein, Mouse, Recombinant (His & Fc Tag)

50412-M03H

Expression host: HEK293 Cells

Mouse TRAIL R2/CD262/TNFRSF10B Protein 11621

DR5 Protein, Mouse, Recombinant (His Tag)

50412-M08H

Expression host: HEK293 Cells

Mouse TRAIL R2/CD262/TNFRSF10B Protein 11622

DR5 Protein, Human, Recombinant (His & Fc Tag)

10465-H03H

Expression host: HEK293 Cells

Human TRAIL R2/CD262/TNFRSF10B Protein 8836
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DR5 Antibody (9)

Application Clonality
Host

Anti-DR5 Antibody

10465-T16

Application: ELISA

Clonality: PAb

Anti-DR5 Antibody

10465-T16

Specificity: Human

Application: ELISA

Clonality: PAb

Anti-DR5 Antibody

50412-RP01

Specificity: Mouse

Application: ELISA

Clonality: PAb

Anti-DR5 Antibody

10465-RP01

Specificity: Human

Application: ELISA

Clonality: PAb

Anti-DR5 Antibody

10465-R102

Specificity: Human

Application: ELISA,FCM

Clonality: MAb

Human TRAIL R2/CD262/TNFRSF10B Flow Cytometry (FC) 5006

Anti-DR5 Antibody (PE)

10465-R102-P

Specificity: Human

Application: FCM

Clonality: MAb

Human TRAIL R2/CD262/TNFRSF10B Flow Cytometry (FC) 2556

Anti-DR5 Antibody

10465-RP02

Specificity: Human

Application: ELISA

Clonality: PAb

Anti-DR5 Antibody

50412-T16

Application: ELISA

Clonality: PAb

Anti-DR5 Antibody

50412-R131

Specificity: Mouse

Application: ELISA

Clonality: MAb

Anti-DR5 Antibody

50412-RP02

Specificity: Mouse

Application: ELISA

Clonality: PAb

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DR5 cDNA Clone (27)

Human
Mouse
Cynomolgus

DR5 qPCR Primer (2)

DR5 Lysate (4)

Tumor necrosis factor receptor superfamily, member 1b, official symbol TNFRSF1B, also known as Death receptor 5, CD262, TNF-related apoptosis-inducing ligand receptor 2 (TRAIL R2), is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF1/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. TRAIL R2/CD262/TNFRSF1B was purified independently as the only receptor for TRAIL detectable on the surface of two different human cell lines that undergo apoptosis upon stimulation with TRAIL. TRAIL R2/CD262/TNFRSF1B contains two extracellular cysteine-rich repeats, typical for TNF receptor (TNFR) family members, and a cytoplasmic death domain. TRAIL R2/CD262/TNFRSF1B mediates apoptosis via the intracellular adaptor molecule FADD/MORT1. TRAIL receptors can signal both death and gene transcription, functions reminiscent of those of TNFR1 and TRAMP, two other members of the death receptor family. Defects in TRAIL R2/CD262/TNFRSF1B may be a cause of head and neck squamous cell carcinomas (HNSCC) also known as squamous cell carcinoma of the head and neck.Immune Checkpoint   Immunotherapy   Cancer Immunotherapy   Targeted Therapy
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Antibody
Gene
qPCR
Lysate
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