All TNF-alpha reagents are produced in house and quality controlled, including 34 TNF-alpha Antibody, 4 TNF-alpha ELISA, 78 TNF-alpha Gene, 1 TNF-alpha IPKit, 1 TNF-alpha Lysate, 11 TNF-alpha Protein, 3 TNF-alpha qPCR. All TNF-alpha reagents are ready to use.
Recombinant TNF-alpha proteins are expressed by E. coli, HEK293 Cells with fusion tags as Native, N-human IgG1-Fc.
TNF-alphaantibodies are validated with different applications, which are FCM, ELISA, ELISA(Cap), WB, ICC/IF, IF, ELISA(Det), Neutralization, IP.
TNF-alphacDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each TNF-alpha of different species, especially GFP tag, OFP tag, FLAG tag and so on. There are three kinds of vectors for choice, cloning vector, expression vector and lentivrial expression vector.
TNF-alphaELISA Kit are quality controlled by 8 internation QC standard which guarantee every ELISA Kit with high quality.
Tumor necrosis factor alpha (TNF-alpha), also known as TNF, TNFA or TNFSF2, is the prototypic cytokine of the TNF superfamily, and is a multifunctional molecule involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. Two receptors, TNF-R1 (TNF receptor type 1; CD120a; p55/60) and TNF-R2 (TNF receptor type 2; CD120b; p75/80), bind to TNF-alpha. TNF-alpha protein is produced mainly by macrophages, and large amounts of this cytokine are released in response to lipopolysaccharide, other bacterial products, and Interleukin-1 (IL-1). TNF-alpha is involved in fighting against the tumorigenesis, thus, is regarded as a molecular insight in cancer treatment.