TLK1 (タンパク質 | 抗体 | cDNA クローン | ELISA キット)

All TLK1 reagents are produced in house and quality controlled, including 1 TLK1 Antibody, 1 TLK1 Gene, 1 TLK1 IP Kit, 1 TLK1 Lysate, 1 TLK1 Protein. All TLK1 reagents are ready to use.

TLK1 の背景知識

Tousled-like kinase 1 (or protein kinase ubiquitous, PKU-beta/TLK1) is a serine/threonine protein kinase that is implicated in chromatin remodeling, DNA replication and mitosis. TLK1 has a function important for proper chromosome segregation and maintenance of diploid cells at mitosis in mammalian cells that could be mediated by reduced phosphorylation of histone H3 and condensation of chromosomes, although other explanations to the phenotype are possible.

TLK1 の参考文献

  • Sillje H.H.W., et al., 2001, Curr. Biol. 11:1068-73.
  • Beausoleil S.A., et al., 2004, Proc. Natl. Acad. Sci. USA. 101:12130-5.
  • Oppermann F.S., et al., 2009, Mol. Cell. Proteomics 8:1751-64.
  • Mayya V., et al., 2009, Sci. Signal. 2: RA46-RA46.