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ST6GAL1 / ST6GAL-I 抗体, ウサギモノクローナル抗体

データシートレビュー関連製品プロトコル
人々 ST6GAL1 抗体製品情報
免疫原:Recombinant Human ST6GAL1 / ST6GAL-I protein (Catalog#11590-H07H)
Clone ID:036
Ig タイプ:Rabbit IgG
濃度:
エンドトキシン:
製剤:0.2 μm filtered solution in PBS with 5% trehalose
調製:This antibody was obtained from a rabbit immunized with purified, recombinant Human ST6GAL1 / ST6GAL-I (rh ST6GAL1 / ST6GAL-I; Catalog#11590-H07H; P15907; Lys27-Cys406).
人々 ST6GAL1 Antibody IHC Application Image
ST6GAL1 / CD75 Antibody, Rabbit MAb, Immunohistochemistry
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Caption:
Immunochemical staining of human ST6GAL1 in human kidney with rabbit monoclonal antibody (5 µg/mL, formalin-fixed paraffin embedded sections).
ST6GAL1 / CD75 Antibody, Rabbit MAb, Immunohistochemistry
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Caption:
Immunochemical staining of human ST6GAL1 in human prostate with rabbit monoclonal antibody (5 µg/mL, formalin-fixed paraffin embedded sections). Positive staining was localized to epithelium.
Other ST6GAL1 Antibody Products
ST6GAL1/ST6GAL-I 背景

Beta-galactoside alpha-2,6-sialyltransferase 1, also known as B-cell antigen CD75, Sialyltransferase 1, CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase 1, ST6GAL1 and SIAT1, is a single-pass type II membrane protein which belongs to the glycosyltransferase 29 family. Sialyltransferases are key enzymes in the biosynthesis of sialoglycoconjugates that catalyze the transfer of sialic residue from its activated form to an oligosaccharidic acceptor. ST6GAL1 / SIAT1 is normally found in the?Golgi?but which can be proteolytically processed to a soluble form. It is involved in the generation of the cell-surface carbohydrate determinants and differentiation antigens HB-6, CDw75, and CD76. β-Galactoside α2,6-sialyltransferases ST6GAL1 and ST6GAL2 are the two unique members of the ST6GAL family described in higher vertebrates. ST6GAL1 / SIAT1 transfers sialic acid from the donor of substrate CMP-sialic acid to galactose containing acceptor substrates.

人々 ST6GAL1/ST6GAL-I 参考文献
  • Collins,B.E. et al., 2006, Nat Immunol. 7(2):199-206.
  • Videira,P.A. et al., 2008, Glycoconj J. 25(3): 259-68.
  • Petit,D. et al., 2010, J Biol Chem. 285(49): 38399-414.
  • Kroes,R.A. et al., 2010, Proc Natl Acad Sci USA.107(28):12646-51.
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    カタログ: 11590-R036-50
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