Src (タンパク質 | 抗体 | cDNA クローン | ELISA キット)

All Src reagents are produced in house and quality controlled, including 1 Src Antibody, 44 Src Gene, 2 Src Lysate, 2 Src Protein, 2 Src qPCR. All Src reagents are ready to use.

Src Protein (2)

Src Antibody (1)

Src cDNA Clone (44)

NM_005417.3

クローニングベクター cDNA 製品

In lentiviral vector

In expression vector

NM_001025395.2

クローニングベクター cDNA 製品

In lentiviral vector

NM_009271.3

クローニングベクター cDNA 製品

In lentiviral vector

Src Lysate (2)

Src の背景知識

Proto-oncogene tyrosine-protein kinase SRC is a hydrophobic protein belonging to the SRC family kinase including nine members that is a family of non-receptor tyrosine kinases. SRC protein may exist in different forms: C-SRC and V-SRC. C-SRC is only activated under certain circumstances where it is required such as growth factor signaling, while V-SRC is a constitutively active as opposed to normal SRC (C-SRC). Thus, V-SRC is an instructive example of an oncogene protein kinase whereas C-SRC is a proto-oncogene protein kinase. Inhibition of SRC with NR2A tyrosine phosphorylation mediated by PSD-95 may contribute to the lithium-induced downregulation of NMDA receptor function and provide neuroprotection against excitotoxicity.

Src の参考文献

  • Juan Ma. et al., 2003, Neuroscience Letters. 348 (3): 185-189.
  • Czernilofsky AP. et al., 1980, Nature. 287: 198-203.
  • Beischlag TV. et al., 2002, Molecular and cellular biology. 22 (12): 4319-33.